5K25

Crystal structure of human phosphatase PRL-2 in complex with the ADP-bound Bateman domain of human magnesium transporter CNNM3

Summary for 5K25

• Entry DOI: 10.2210/pdb5k25/pdb
• Related: 5K22 5K23 5K24
• Descriptor: Protein tyrosine phosphatase type IVA 2, Metal transporter CNNM3, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: complex, phosphatase, magnesium transporter, protein binding, hydrolase, hydrolase-transporter protein-protein binding complex, hydrolase/transporter protein/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 40116.69

Authors

Gulerez, I.,Kozlov, G.,Gehring, K. (deposition date: 2016-05-18, release date: 2016-10-12, Last modification date: 2018-10-03)

• Primary citation: Zhang, H.,Kozlov, G.,Li, X.,Wu, H.,Gulerez, I.,Gehring, K.; PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.; Sci Rep, 7:48-48, 2017; PubMed: 28246390; DOI: 10.1038/s41598-017-00147-2

Experimental method

X-RAY DIFFRACTION (3.05 Å)