crystal structure of the UBA domain from Cbl-b ubiquitin ligase in complex with ubiquitin

Summary for 2OOB

Related2OO9 2OOA
DescriptorE3 ubiquitin-protein ligase CBL-B, Ubiquitin (3 entities in total)
Functional Keywordsprotein-protein complex, ligase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q13191
Total number of polymer chains2
Total molecular weight14233.21
Kozlov, G.,Gehring, K. (deposition date: 2007-01-25, release date: 2007-02-06, Last modification date: 2011-07-13)
Primary citation
Peschard, P.,Kozlov, G.,Lin, T.,Mirza, I.A.,Berghuis, A.M.,Lipkowitz, S.,Park, M.,Gehring, K.
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.
Mol.Cell, 27:474-485, 2007
PubMed: 17679095 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2007.06.023
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.256605.0%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report