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5TFP
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Crystal Structure of the SETDB2 Amino Terminal Domain
分子名称: GLYCEROL, Histone-lysine N-methyltransferase SETDB2, L(+)-TARTARIC ACID
著者Khorasanizadeh, S, Kim, Y.
登録日2016-09-26
公開日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a helical dimerization domain in SETDB2 lysine methyltransferase
To Be Published
1QRJ
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Solution structure of htlv-i capsid protein
分子名称: HTLV-I CAPSID PROTEIN
著者Khorasanizadeh, S, Campos-Olivas, R, Clark, C.A, Summers, M.F.
登録日1999-06-14
公開日1999-07-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Sequence-specific 1H, 13C and 15N chemical shift assignment and secondary structure of the HTLV-I capsid protein.
J.Biomol.NMR, 14, 1999
1A6Y
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REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX
分子名称: DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ...
著者Zhao, Q, Khorasanizadeh, S, Rastinejad, F.
登録日1998-03-04
公開日1998-10-21
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural elements of an orphan nuclear receptor-DNA complex.
Mol.Cell, 1, 1998
2H1E
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BU of 2h1e by Molmil
Tandem chromodomains of budding yeast CHD1
分子名称: Chromo domain protein 1
著者Flanagan IV, J.F, Khorasanizadeh, S.
登録日2006-05-16
公開日2007-03-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Implications of Evolutionary Differences in CHD Double Chromodomains.
J.Mol.Biol., 369, 2007
4O9I
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Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding
分子名称: Chromodomain-helicase-DNA-binding protein 4
著者Wiggs, K.R, Chruszcz, M, Su, X, Minor, W, Khorasanizadeh, S.
登録日2014-01-02
公開日2015-07-08
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding
TO BE PUBLISHED
2M2L
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Solution structure of Entamoeba histolytica HP1 chromodomain
分子名称: Putative uncharacterized protein
著者Wiggins, K.R, Ren, X, Ali, I.K.M, Petri, W.A, Khorasanizadeh, S.
登録日2012-12-28
公開日2014-05-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of putative readers of epigenetic methyl-marks from Entamoeba histolytica
To be Published
6E3S
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BU of 6e3s by Molmil
Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist PT2385
分子名称: 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
登録日2018-07-15
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3T
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Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist T1001
分子名称: (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
登録日2018-07-15
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3U
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Crystal Structure of the Heterodimeric HIF-2 Complex with Agonist M1001
分子名称: 3-{[2-(pyrrolidin-1-yl)phenyl]amino}-1H-1lambda~6~,2-benzothiazole-1,1-dione, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Wu, D, Su, X, Lu, J, Li, S, Hood, B, Vasile, S, Potluri, N, Diao, X, Kim, Y, Khorasanizadeh, S, Rastinejad, F.
登録日2018-07-15
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
1DSZ
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BU of 1dsz by Molmil
STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
分子名称: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ...
著者Rastinejad, F, Wagner, T, Zhao, Q, Khorasanizadeh, S.
登録日2000-01-10
公開日2000-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
EMBO J., 19, 2000
1MT6
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BU of 1mt6 by Molmil
Structure of histone H3 K4-specific methyltransferase SET7/9 with AdoHcy
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SET9
著者Jacobs, S.A, Harp, J.M, Devarakonda, S, Kim, Y, Rastinejad, F, Khorasanizadeh, S.
登録日2002-09-20
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1MUF
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BU of 1muf by Molmil
Structure of histone H3 K4-specific methyltransferase SET7/9
分子名称: SET9
著者Jacobs, S.A, Harp, J.M, Devarakonda, S, Kim, Y, Rastinejad, F, Khorasanizadeh, S.
登録日2002-09-23
公開日2002-11-06
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1OT7
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BU of 1ot7 by Molmil
Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR
分子名称: 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile Acid Receptor, ISO-URSODEOXYCHOLIC ACID, ...
著者Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F.
登録日2003-03-21
公開日2004-03-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OSV
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STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR
分子名称: 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile acid receptor, Nuclear receptor coactivator 2
著者Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F.
登録日2003-03-20
公開日2004-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
3M9Q
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Drosophila MSL3 chromodomain
分子名称: Protein male-specific lethal-3
著者Kim, D, Huang, P, Rastinejad, F, Khorasanizadeh, S.
登録日2010-03-22
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
3OA6
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Human MSL3 Chromodomain bound to DNA and H4K20me1 peptide
分子名称: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), H4 peptide monomethylated at lysine 20, ...
著者Kim, D, Huang, P, Rastinejad, F, Khorasanizadeh, S.
登録日2010-08-04
公開日2010-08-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
3P7J
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BU of 3p7j by Molmil
Drosophila HP1a chromo shadow domain
分子名称: GLYCEROL, Heterochromatin protein 1
著者Kim, D, Chruszcz, M, Minor, W, Khorasanizadeh, S.
登録日2010-10-12
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners.
Chembiochem, 12, 2011
1KNA
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Chromo domain of HP1 complexed with histone H3 tail containing dimethyllysine 9.
分子名称: HETEROCHROMATIN PROTEIN 1, METHYLATED Histone H3
著者Jacobs, S.A, Khorasanizadeh, S.
登録日2001-12-18
公開日2002-03-20
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1KNE
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Chromo domain of HP1 complexed with histone H3 tail containing trimethyllysine 9
分子名称: HETEROCHROMATIN PROTEIN 1, Trimethylated Histone H3
著者Jacobs, S.A, Khorasanizadeh, S.
登録日2001-12-18
公開日2002-03-20
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1PDQ
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Polycomb chromodomain complexed with the histone H3 tail containing trimethyllysine 27.
分子名称: Histone H3.3, Polycomb protein
著者Fischle, W, Wang, Y, Jacobs, S.A, Kim, Y, Allis, C.D, Khorasanizadeh, S.
登録日2003-05-20
公開日2003-08-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
Genes Dev., 17, 2003
1Q3L
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Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.
分子名称: Heterochromatin protein 1, Histone H3
著者Jacobs, S.A, Khorasanizadeh, S.
登録日2003-07-30
公開日2004-10-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9
To be Published
2B2W
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Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2T
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Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2U
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Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2Y
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Tandem chromodomains of human CHD1
分子名称: Chromodomain-helicase-DNA-binding protein 1
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005

 

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