1MT6

Structure of histone H3 K4-specific methyltransferase SET7/9 with AdoHcy

Summary for 1MT6

Related1MUF
DescriptorSET9, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywordsset domain, histone lysine methyltransferase, adohcy, knot, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q8WTS6
Total number of polymer chains1
Total molecular weight31534.82
Authors
Jacobs, S.A.,Harp, J.M.,Devarakonda, S.,Kim, Y.,Rastinejad, F.,Khorasanizadeh, S. (deposition date: 2002-09-20, release date: 2002-11-06, Last modification date: 2011-07-13)
Primary citation
Jacobs, S.A.,Harp, J.M.,Devarakonda, S.,Kim, Y.,Rastinejad, F.,Khorasanizadeh, S.
The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9:833-838, 2002
PubMed: 12389038 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.260363.6%13.1%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1mt6
no rotation
Molmil generated image of 1mt6
rotated about x axis by 90°
Molmil generated image of 1mt6
rotated about y axis by 90°