5IE1
 
 | | Crystal structure of BACE1 in complex with 3-(2-amino-6-(o-tolyl)quinolin-3-yl)-N-(3,3-dimethylbutyl)propanamide | | 分子名称: | 3-[2-amino-6-(2-methylphenyl)quinolin-3-yl]-N-(3,3-dimethylbutyl)propanamide, Beta-secretase 1, GLYCEROL, ... | | 著者 | Jordan, J.B, Whittington, D.A, Bartberger, M.D, Sickmier, E.A, Chen, K, Cheng, Y, Judd, T. | | 登録日 | 2016-02-24 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of beta-Secretase.
J.Med.Chem., 59, 2016
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2KEF
 | | Solution NMR structures of human hepcidin at 325K | | 分子名称: | Hepcidin | | 著者 | Jordan, J.B, Poppe, L, Hainu, M, Arvedson, T, Syed, R, Li, V, Kohno, H, Kim, H, Miranda, L.P, Cheetham, J, Sasu, B.J. | | 登録日 | 2009-01-29 | | 公開日 | 2009-06-23 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hepcidin revisited, disulfide connectivity, dynamics, and structure.
J.Biol.Chem., 284, 2009
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6CHC
 | | JzTx-V toxin peptide, wild-type | | 分子名称: | Beta/kappa-theraphotoxin-Cg2a | | 著者 | Jordan, J.B. | | 登録日 | 2018-02-22 | | 公開日 | 2018-05-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V.
PLoS ONE, 13, 2018
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6CGW
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2LZG
 | | NMR Structure of Mdm2 (6-125) with Pip-1 | | 分子名称: | E3 ubiquitin-protein ligase Mdm2, [(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid | | 著者 | Michelsen, K.B, Jordan, J.B, Lewis, J, Long, A.M, Yang, E, Rew, Y, Zhou, J, Yakowec, P, Schnier, P.D, Huang, X, Poppe, L. | | 登録日 | 2012-10-02 | | 公開日 | 2012-11-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ordering of the N-Terminus of Human MDM2 by Small Molecule Inhibitors.
J.Am.Chem.Soc., 134, 2012
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2F55
 | | Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna | | 分子名称: | 5'-D(P*(DU)P*(DU)P*(DU))-3', 5'-D(P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU))-3', SULFATE ION, ... | | 著者 | Lu, J.Z, Jordan, J.B, Sakon, J. | | 登録日 | 2005-11-25 | | 公開日 | 2005-12-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus
J.Biol.Chem., 281, 2006
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5I3V
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5I3X
 | | Crystal structure of BACE1 in complex with aminoquinoline inhibitor 6 | | 分子名称: | Beta-secretase 1, GLYCEROL, N-(1-{3-[2-(2-amino-3-{3-[(3,3-dimethylbutyl)amino]-3-oxopropyl}quinolin-6-yl)phenyl]prop-2-yn-1-yl}cyclopropyl)-4-fluorobenzamide | | 著者 | Whittington, D.A, Long, A.M. | | 登録日 | 2016-02-11 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of beta-Secretase.
J.Med.Chem., 59, 2016
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5I3W
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5I3Y
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3H0T
 | | Hepcidin-Fab complex | | 分子名称: | Fab fragment, Heavy chain, Light chain, ... | | 著者 | Syed, R, Li, V. | | 登録日 | 2009-04-10 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Hepcidin revisited, disulfide connectivity, dynamics, and structure.
J.Biol.Chem., 284, 2009
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5IN4
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5IN5
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4HBM
 | | Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors | | 分子名称: | E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-hydroxybutan-2-yl]-2-oxopiperidin-3-yl}acetic acid | | 著者 | Huang, X. | | 登録日 | 2012-09-28 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Ordering of the N-terminus of human MDM2 by small molecule inhibitors.
J.Am.Chem.Soc., 134, 2012
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1NG8
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1NT6
 | | F1-Gramicidin C In Sodium Dodecyl Sulfate Micelles (NMR) | | 分子名称: | GRAMICIDIN C | | 著者 | Townsley, L.E, Fletcher, T.G, Hinton, J.F. | | 登録日 | 2003-01-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure, Cation Binding, Transport, and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles.
Biochemistry, 42, 2003
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1NT5
 | | F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR) | | 分子名称: | GRAMICIDIN A | | 著者 | Townsley, L.E, Fletcher, T.G, Hinton, J.F. | | 登録日 | 2003-01-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure, Cation Binding, Transport, and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles.
Biochemistry, 42, 2003
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