2F55

Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna

Summary for 2F55

• Entry DOI: 10.2210/pdb2f55/pdb
• Related: 1A1V
• Descriptor: 5'-D(P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU))-3', 5'-D(P*(DU)P*(DU)P*(DU))-3', polyprotein, ... (5 entities in total)
• Functional Keywords: hydrolase/dna, hydrolase-dna complex
• Biological source: Hepatitis C virus
• Total number of polymer chains: 5
• Total formula weight: 144460.62

Authors

Lu, J.Z.,Jordan, J.B.,Sakon, J. (deposition date: 2005-11-25, release date: 2005-12-06, Last modification date: 2023-08-23)

• Primary citation: Mackintosh, S.G.,Lu, J.Z.,Jordan, J.B.,Harrison, M.K.,Sikora, B.,Sharma, S.D.,Cameron, C.E.,Raney, K.D.,Sakon, J.; Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus; J.Biol.Chem., 281:3528-3535, 2006; PubMed: 16306038; DOI: 10.1074/jbc.M512100200

Experimental method

X-RAY DIFFRACTION (3.3 Å)