2J0O
 
 | | Shigella Flexneri IpaD | | Descriptor: | GLYCEROL, INVASIN IPAD | | Authors: | Johnson, S, Roversi, P, Lea, S.M. | | Deposit date: | 2006-08-04 | | Release date: | 2006-11-02 | | Last modified: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
J. Biol. Chem., 282, 2007
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2J0N
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2J9T
 | | BipD of Burkholderia Pseudomallei | | Descriptor: | BORIC ACID, CITRATE ANION, MEMBRANE ANTIGEN | | Authors: | Johnson, S, Roversi, P, Field, T, Deane, J.E, Galyov, E, Lea, S.M. | | Deposit date: | 2006-11-16 | | Release date: | 2006-11-20 | | Last modified: | 2014-10-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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2JAA
 | | SeMet substituted Shigella Flexneri Ipad | | Descriptor: | INVASIN IPAD | | Authors: | Johnson, S, Roversi, P, Espina, M, Olive, A, Deane, J.E, Birket, S, Field, T, Picking, W.D, Blocker, A.J, Galyov, E.E, Picking, W.L, Lea, S.M. | | Deposit date: | 2006-11-24 | | Release date: | 2006-11-30 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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8UCS
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5NQY
 | | Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309. | | Descriptor: | Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001 | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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5NQZ
 | | Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 309. | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein, ... | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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7AKV
 | | The cryo-EM structure of the Vag8-C1 inhibitor complex | | Descriptor: | Plasma protease C1 inhibitor, Vag8 | | Authors: | Johnson, S, Lea, S.M, Deme, J.C, Furlong, E, Dhillon, A. | | Deposit date: | 2020-10-02 | | Release date: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex.
Mbio, 12, 2021
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6F2D
 | | A FliPQR complex forms the core of the Salmonella type III secretion system export apparatus. | | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | | Authors: | Johnson, S, Kuhlen, L, Abrusci, P, Lea, S.M. | | Deposit date: | 2017-11-24 | | Release date: | 2018-07-04 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure of the core of the type III secretion system export apparatus.
Nat. Struct. Mol. Biol., 25, 2018
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2VJ2
 | | Human Jagged-1, domains DSL and EGFs1-3 | | Descriptor: | D-MALATE, JAGGED-1 | | Authors: | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | | Deposit date: | 2007-12-06 | | Release date: | 2008-07-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
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2VJ3
 | | Human Notch-1 EGFs 11-13 | | Descriptor: | CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ... | | Authors: | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Lea, S.M. | | Deposit date: | 2007-12-06 | | Release date: | 2008-07-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
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5NQP
 | | Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 151. | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001, ... | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-20 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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5NQX
 | | Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 294. | | Descriptor: | Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein | | Authors: | Johnson, S, Jongerius, I, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.66 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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2IXR
 | | BipD of Burkholderia Pseudomallei | | Descriptor: | MEMBRANE ANTIGEN | | Authors: | Roversi, P, Johnson, S, Field, T, Deane, J.E, Galyov, E.E, Lea, S.M. | | Deposit date: | 2006-07-10 | | Release date: | 2006-11-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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4V2K
 | | Crystal structure of the thiosulfate dehydrogenase TsdA in complex with thiosulfate | | Descriptor: | HEME C, THIOSULFATE, THIOSULFATE DEHYDROGENASE | | Authors: | Grabarczyk, D.B, Chappell, P.E, Eisel, B, Johnson, S, Lea, S.M, Berks, B.C. | | Deposit date: | 2014-10-10 | | Release date: | 2015-02-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Mechanism of Thiosulfate Oxidation in the Soxa Family of Cysteine-Ligated Cytochromes
J.Biol.Chem., 290, 2015
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4UWQ
 | | Crystal structure of the disulfide-linked complex of the thiosulfodyrolase SoxB with the carrier-protein SoxYZ from Thermus thermophilus | | Descriptor: | MANGANESE (II) ION, SOXY PROTEIN, SOXZ, ... | | Authors: | Grabarczyk, D.B, Chappell, P.E, Johnson, S, Stelzl, L.S, Lea, S.M, Berks, B.C. | | Deposit date: | 2014-08-14 | | Release date: | 2015-12-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.28 Å) | | Cite: | Structural Basis for Specificity and Promiscuity in a Carrier Protein/Enzyme System from the Sulfur Cycle
Proc.Natl.Acad.Sci.USA, 112, 2015
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4TT9
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6S3S
 | | Structure of the FliPQR complex from the flagellar type 3 secretion system of Vibrio mimicus. | | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | | Deposit date: | 2019-06-25 | | Release date: | 2020-03-25 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion.
Nat Commun, 11, 2020
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6S3R
 | | Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. | | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | | Deposit date: | 2019-06-25 | | Release date: | 2020-03-25 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion.
Nat Commun, 11, 2020
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6S3L
 | | Structure of the core of the flagellar export apparatus from Vibrio mimicus, the FliPQR-FlhB complex. | | Descriptor: | Flagellar biosynthetic protein FlhB, Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, ... | | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | | Deposit date: | 2019-06-25 | | Release date: | 2020-03-25 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion.
Nat Commun, 11, 2020
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7AMY
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5HCC
 | | Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3. | | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Jore, M.M, Johnson, S, Lea, S.M. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
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5HCD
 | | Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ... | | Authors: | Jore, M.M, Johnson, S, Lea, S.M. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
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5HCE
 | | Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus appendiculatus RaCI1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Complement C5, ... | | Authors: | Jore, M.M, Johnson, S, Lea, S.M. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
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8HC1
 | | CryoEM structure of Helicobacter pylori UreFD/urease complex | | Descriptor: | Urease accessory protein UreF, Urease accessory protein UreH, Urease subunit alpha, ... | | Authors: | Nim, Y.S, Fong, I.Y.H, Deme, J, Tsang, K.L, Caesar, J, Johnson, S, Wong, K.B, Lea, S.M. | | Deposit date: | 2022-11-01 | | Release date: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Delivering a toxic metal to the active site of urease.
Sci Adv, 9, 2023
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