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5HCD

Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2

Summary for 5HCD
Entry DOI10.2210/pdb5hcd/pdb
DescriptorComplement C5, Complement inhibitor, Rhipicephalus microplus RaCI2, ... (6 entities in total)
Functional Keywordscomplement, inflammation, inhibitor, tick, immune system
Biological sourceOrnithodoros moubata (Soft tick)
More
Total number of polymer chains4
Total formula weight213905.39
Authors
Jore, M.M.,Johnson, S.,Lea, S.M. (deposition date: 2016-01-04, release date: 2016-03-30, Last modification date: 2024-01-10)
Primary citationJore, M.M.,Johnson, S.,Sheppard, D.,Barber, N.M.,Li, Y.I.,Nunn, M.A.,Elmlund, H.,Lea, S.M.
Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23:378-386, 2016
Cited by
PubMed: 27018802
DOI: 10.1038/nsmb.3196
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.98 Å)
Structure validation

217705

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