5HCD

Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004866	molecular_function	endopeptidase inhibitor activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006954	biological_process	inflammatory response
A	0006956	biological_process	complement activation
B	0004866	molecular_function	endopeptidase inhibitor activity
C	0005576	cellular_component	extracellular region
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity
D	0005576	cellular_component	extracellular region
D	0035821	biological_process	modulation of process of another organism
D	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS01177
Number of Residues	35
Details	ANAPHYLATOXIN_1 Anaphylatoxin domain signature. CCydGacvnnde.TCEqraarisl.GprCikafte.CC

Chain	Residue	Details
A	CYS698-CYS732

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:23625922, ECO:0007744|PDB:3ZUO

Chain	Residue	Details
C	ARG54
C	TRP87
C	ARG107
C	HIS119
C	ASP121

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:23625922, ECO:0007744|PDB:3ZUI

Chain	Residue	Details
C	THR85

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN1115

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952

Chain	Residue	Details
A	ASN1630

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