7AKV

The cryo-EM structure of the Vag8-C1 inhibitor complex

Summary for 7AKV

Entry DOI	10.2210/pdb7akv/pdb
EMDB information	11814
Descriptor	Plasma protease C1 inhibitor, Vag8 (2 entities in total)
Functional Keywords	complex bacterial protein human protein immune system inhibitor, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	136273.81
Authors	Johnson, S.,Lea, S.M.,Deme, J.C.,Furlong, E.,Dhillon, A. (deposition date: 2020-10-02, release date: 2021-06-16)
Primary citation	Dhillon, A.,Deme, J.C.,Furlong, E.,Roem, D.,Jongerius, I.,Johnson, S.,Lea, S.M. Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex. Mbio, 12:-, 2021 Cited by PubMed: 33758081 DOI: 10.1128/mBio.02823-20 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation