5NQX
Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 294.
Summary for 5NQX
| Entry DOI | 10.2210/pdb5nqx/pdb |
| Descriptor | Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein (1 entity in total) |
| Functional Keywords | meningitis, vaccine, complement, chimeric, immune system |
| Biological source | Neisseria meningitidis MC58 More |
| Total number of polymer chains | 5 |
| Total formula weight | 145922.77 |
| Authors | Johnson, S.,Jongerius, I.,Lea, S.M.,Tang, C.M. (deposition date: 2017-04-21, release date: 2018-02-28, Last modification date: 2024-01-17) |
| Primary citation | Hollingshead, S.,Jongerius, I.,Exley, R.M.,Johnson, S.,Lea, S.M.,Tang, C.M. Structure-based design of chimeric antigens for multivalent protein vaccines. Nat Commun, 9:1051-1051, 2018 Cited by PubMed: 29535307DOI: 10.1038/s41467-018-03146-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.66 Å) |
Structure validation
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