5NQY

Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309.

Summary for 5NQY

Entry DOI	10.2210/pdb5nqy/pdb
Descriptor	Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001 (2 entities in total)
Functional Keywords	meningitis, vaccine, complement, chimeric, immune system
Biological source	Neisseria meningitidis More
Total number of polymer chains	1
Total formula weight	29319.63
Authors	Johnson, S.,Hollingshead, S.,Lea, S.M.,Tang, C.M. (deposition date: 2017-04-21, release date: 2018-02-28, Last modification date: 2024-01-17)
Primary citation	Hollingshead, S.,Jongerius, I.,Exley, R.M.,Johnson, S.,Lea, S.M.,Tang, C.M. Structure-based design of chimeric antigens for multivalent protein vaccines. Nat Commun, 9:1051-1051, 2018 Cited by PubMed: 29535307 DOI: 10.1038/s41467-018-03146-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation