1E5D
| RUBREDOXIN OXYGEN:OXIDOREDUCTASE (ROO) FROM ANAEROBE DESULFOVIBRIO GIGAS | 分子名称: | FLAVIN MONONUCLEOTIDE, MU-OXO-DIIRON, OXYGEN MOLECULE, ... | 著者 | Frazao, C, Silva, G, Gomes, C.M, Matias, P, Coelho, R, Sieker, L, Macedo, S, Liu, M.Y, Oliveira, S, Teixeira, M, Xavier, A.V, Rodrigues-Pousada, C, Carrondo, M.A, Le Gall, J. | 登録日 | 2000-07-24 | 公開日 | 2000-11-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of a Dioxygen Reduction Enzyme from Desulfovibrio Gigas Nat.Struct.Biol., 7, 2000
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4TYA
| An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | 4-(trifluoromethyl)benzoic acid, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TVX
| Crystal structure of the E. coli CRISPR RNA-guided surveillance complex, Cascade | 分子名称: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | 著者 | Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B. | 登録日 | 2014-06-28 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli. Science, 345, 2014
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4U7O
| Active histidine kinase bound with ATP | 分子名称: | AMP PHOSPHORAMIDATE, Histidine protein kinase sensor protein | 著者 | Cai, Y, Hu, X, Sang, J. | 登録日 | 2014-07-31 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Conformational dynamics of the essential sensor histidine kinase WalK. Acta Crystallogr D Struct Biol, 73, 2017
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4TXS
| An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | (4-hydroxyphenyl)acetonitrile, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-07 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TYT
| Crystal Structure of BcII metallo-beta-lactamase in complex with ML302F | 分子名称: | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase 2, GLYCEROL, ... | 著者 | Brem, J, van Berkel, S.S, McDonough, M.A, Schofield, C.J. | 登録日 | 2014-07-09 | 公開日 | 2014-11-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Rhodanine hydrolysis leads to potent thioenolate mediated metallo-beta-lactamase inhibition. Nat.Chem., 6, 2014
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4TY8
| An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | 6-methyl-2H-chromen-2-one, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4U7N
| Inactive structure of histidine kinase | 分子名称: | Histidine protein kinase sensor protein | 著者 | Cai, Y, Hu, X, Sang, J. | 登録日 | 2014-07-31 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Conformational dynamics of the essential sensor histidine kinase WalK. Acta Crystallogr D Struct Biol, 73, 2017
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4UIM
| crystal structure of quinine-dependent Fab 314.3 | 分子名称: | FAB 314.3, SULFATE ION | 著者 | Zhu, J, Zhu, J, Bougie, D.W, Aster, R.H, Springer, T.A. | 登録日 | 2015-03-30 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3 Blood, 126, 2015
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4UIK
| crystal structure of quinine-dependent Fab 314.1 | 分子名称: | FAB 314.1 | 著者 | Zhu, J, Zhu, J, Bougie, D.W, Aster, R.H, Springer, T.A. | 登録日 | 2015-03-30 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3 Blood, 126, 2015
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4UQ3
| Crystal structure of HLA-A0201 in complex with an azobenzene- containing peptide | 分子名称: | AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. | 登録日 | 2014-06-19 | 公開日 | 2014-09-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. Angew. Chem. Int. Ed. Engl., 53, 2014
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4UQ2
| Crystal structure of HLA-A1101 in complex with an azobenzene- containing peptide | 分子名称: | AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. | 登録日 | 2014-06-19 | 公開日 | 2014-09-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Bioorthogonal Cleavage and Exchange of Major Histocompatibility Complex Ligands by Employing Azobenzene-Containing Peptides. Angew.Chem.Int.Ed.Engl., 53, 2014
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4UF0
| Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid. | 分子名称: | 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, FE (II) ION, ... | 著者 | Srikannathasan, V, Johansson, C, Gileadi, C, Tobias, K, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. | 登録日 | 2014-12-22 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12, 2016
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4UIN
| crystal structure of quinine-dependent Fab 314.3 with quinine | 分子名称: | FAB 314.3, Quinine | 著者 | Zhu, J, Zhu, J, Bougie, D.W, Aster, R.H, Springer, T.A. | 登録日 | 2015-03-30 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3 Blood, 126, 2015
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4UIL
| crystal structure of quinine-dependent Fab 314.1 with quinine | 分子名称: | FAB 314.1, Quinine | 著者 | Zhu, J, Zhu, J, Bougie, D.W, Aster, R.H, Springer, T.A. | 登録日 | 2015-03-30 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.853 Å) | 主引用文献 | Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3 Blood, 126, 2015
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4UIJ
| Crystal structure of the BTB domain of KCTD13 | 分子名称: | BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1, CHLORIDE ION | 著者 | Pinkas, D.M, Sanvitale, C.E, Sorell, F.J, Solcan, N, Goubin, S, Canning, P, Williams, E, Chaikuad, A, Dixon Clarke, S.E, Tallant, C, Fonseca, M, Chalk, R, Doutch, J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2015-03-30 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases. Biochem. J., 474, 2017
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4UVK
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4UT3
| X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | 著者 | Zeh Silva, M, Kopec, J, Fotinou, D, Steiner, R.A. | 登録日 | 2014-07-17 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling. Embo J., 35, 2016
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4W8P
| Crystal structure of RIAM TBS1 in complex with talin R7R8 domains | 分子名称: | 1,2-ETHANEDIOL, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 | 著者 | Chang, Y.C.E, Zhang, H, Wu, J. | 登録日 | 2014-08-25 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling. Structure, 22, 2014
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4UUU
| 1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM | 分子名称: | 1,2-ETHANEDIOL, CYSTATHIONINE BETA-SYNTHASE, S-ADENOSYLMETHIONINE | 著者 | Kopec, J, McCorvie, T.J, Fitzpatrick, F, Strain-Damerell, C, Froese, D.S, Tallant, C, Burgess-Brown, N, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | 登録日 | 2014-07-31 | 公開日 | 2014-08-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation. J.Biol.Chem., 289, 2014
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4W9Y
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4V7P
| Recognition of the amber stop codon by release factor RF1. | 分子名称: | 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Korostelev, A, Zhu, J, Asahara, H, Noller, H.F. | 登録日 | 2010-04-29 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.62 Å) | 主引用文献 | Recognition of the amber UAG stop codon by release factor RF1. Embo J., 29, 2010
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4V3J
| Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN | 著者 | Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | 登録日 | 2014-10-20 | 公開日 | 2016-01-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4UY1
| Novel pyrazole series of group X Secretory Phospholipase A2 (sPLA2-X) inhibitors | 分子名称: | 5-(2,5-DIMETHYL-3-THIENYL)-1H-PYRAZOLE-3-CARBOXAMIDE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sandmark, J, Oster, L, Hallberg, K, Bodin, C, Chen, H. | 登録日 | 2014-08-28 | 公開日 | 2014-10-15 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Novel Pyrazole Series of Group X Secreted Phospholipase A2 Inhibitor (Spla2X) Via Fragment Based Virtual Screening Bioorg.Med.Chem.Lett., 24, 2014
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4V00
| Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MONOTREME LACTATING PROTEIN | 著者 | Enjapoori, A.K, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | 登録日 | 2014-09-10 | 公開日 | 2015-09-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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