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7SJ0
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BU of 7sj0 by Molmil
Antibody A7V3 bound to N-terminal domain of the spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, A7V3 Fab heavy chain, A7V3 Fab light chain, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-10-15
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Antibody A7V3 bound to N-terminal domain of the spike
To Be Published
8CW9
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BU of 8cw9 by Molmil
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
Immunity, 55, 2022
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Hsieh, C.-L, McLellan, J.S, Rush, S.A.
Deposit date:2022-01-16
Release date:2022-09-14
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7LVW
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BU of 7lvw by Molmil
Structure of RSV F in Complex with VHH Cl184
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-02-26
Release date:2021-03-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7LVU
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BU of 7lvu by Molmil
Structure of RSV F-directed VHH Cl184
Descriptor: F-VHH-Cl184
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-02-26
Release date:2021-03-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7SEJ
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BU of 7sej by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 subunit, Fusion glycoprotein F2 subunit
Authors:Hsieh, C.-L, Rush, S.A, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-29
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8U1G
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BU of 8u1g by Molmil
Prefusion-stabilized SARS-CoV-2 S2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-08-31
Release date:2024-01-24
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge.
Nat Commun, 15, 2024
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-27
Release date:2024-01-17
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
6XKL
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BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
Deposit date:2020-06-26
Release date:2020-07-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
7TL0
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BU of 7tl0 by Molmil
Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-01-17
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7SEM
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BU of 7sem by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022

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PDB entries from 2024-10-30

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