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6Y95
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BU of 6y95 by Molmil
Ca2+-free Calmodulin mutant N53I
分子名称: Calmodulin
著者Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
登録日2020-03-06
公開日2020-04-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y94
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BU of 6y94 by Molmil
Ca2+-bound Calmodulin mutant N53I
分子名称: CALCIUM ION, Calmodulin
著者Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
登録日2020-03-06
公開日2020-04-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y4P
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BU of 6y4p by Molmil
Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
分子名称: CALCIUM ION, Calmodulin-1, Ryanodine receptor 2
著者Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
登録日2020-02-21
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.13325572 Å)
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6Y4O
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BU of 6y4o by Molmil
Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
分子名称: CALCIUM ION, Calmodulin-2, Ryanodine receptor 2
著者Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
登録日2020-02-21
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.83549082 Å)
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
6GDL
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BU of 6gdl by Molmil
Calmodulin mutant - F141L apo-form Unstructured C-domain
分子名称: Calmodulin-1
著者Holt, C, Overgaard, M.T, Wimmer, R.
登録日2018-04-23
公開日2018-10-17
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1UZ2
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BU of 1uz2 by Molmil
The Cys121Ser Mutant of Beta-Lactoglobulin
分子名称: BETA-LACTOGLOBULIN
著者McNae, I, Jayat, D, Haertle, T, Holt, C, Sawyer, L.
登録日2004-03-03
公開日2004-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A recombinant C121S mutant of bovine beta-lactoglobulin is more susceptible to peptic digestion and to denaturation by reducing agents and heating.
Biochemistry, 43, 2004
6GDK
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BU of 6gdk by Molmil
Calcium bound form of human calmodulin mutant F141L
分子名称: CALCIUM ION, Calmodulin-1
著者Grachov, O, Holt, C, Overgaard, M.T, Wimmer, R.
登録日2018-04-23
公開日2018-10-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1GXA
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BU of 1gxa by Molmil
BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL AND PALMITIC ACID, TRIGONAL LATTICE Z
分子名称: BETA-LACTOGLOBULIN, PALMITIC ACID
著者Kontopidis, G, Sawyer, L.
登録日2002-04-01
公開日2002-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
1GX8
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BU of 1gx8 by Molmil
BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL, TRIGONAL LATTICE Z
分子名称: BETA-LACTOGLOBULIN, RETINOL
著者Kontopidis, G, Sawyer, L.
登録日2002-03-29
公開日2002-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
1GX9
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BU of 1gx9 by Molmil
BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOIC ACID, TRIGONAL LATTICE Z
分子名称: BETA-LACTOGLOBULIN, RETINOIC ACID
著者Kontopidis, G, Sawyer, L.
登録日2002-03-29
公開日2002-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
6U3D
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BU of 6u3d by Molmil
1.75 Angstrom crystal structure of the N53I Ca-CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6U3A
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BU of 6u3a by Molmil
1.65 Angstrom crystal structure of the N97S Ca-CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, SODIUM ION, ...
著者Wang, K, Van Petegem, F.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6U3B
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BU of 6u3b by Molmil
1.7 Angstrom crystal structure of the Q135P Ca-CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6U39
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BU of 6u39 by Molmil
2.4 Angstrom crystal structure of the D129G Ca-CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6DAF
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BU of 6daf by Molmil
2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAE
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BU of 6dae by Molmil
2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Lu, J, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAD
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BU of 6dad by Molmil
1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAH
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BU of 6dah by Molmil
2.5 Angstrom crystal structure of the N97S CaM mutant
分子名称: CALCIUM ION, Calmodulin-1
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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件を2024-04-24に公開中

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