6U39
2.4 Angstrom crystal structure of the D129G Ca-CaM:CaV1.2 IQ domain complex
Summary for 6U39
Entry DOI | 10.2210/pdb6u39/pdb |
Descriptor | Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | membrane protein, calcium-binding protein-membrane protein complex, calcium-binding protein/membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 20 |
Total formula weight | 210985.06 |
Authors | Wang, K.,Van Petegem, F. (deposition date: 2019-08-21, release date: 2020-02-19, Last modification date: 2023-10-11) |
Primary citation | Wang, K.,Brohus, M.,Holt, C.,Overgaard, M.T.,Wimmer, R.,Van Petegem, F. Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding. J. Physiol. (Lond.), 598:1169-1186, 2020 Cited by PubMed: 32012279DOI: 10.1113/JP279307 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report