2P8R
 
 | | Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 carrying R2303K mutant | | Descriptor: | Pre-mRNA-splicing factor Prp8 | | Authors: | Zhang, L, Shen, J, Guarnieri, M.T, Heroux, A, Yang, K, Zhao, R. | | Deposit date: | 2007-03-22 | | Release date: | 2007-05-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Protein Sci., 16, 2007
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2P87
 | | Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 | | Descriptor: | Pre-mRNA-splicing factor Prp8 | | Authors: | Zhang, L, Shen, J, Guarnieri, M.T, Heroux, A, Yang, K, Zhao, R. | | Deposit date: | 2007-03-21 | | Release date: | 2007-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Protein Sci., 16, 2007
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2R0Y
 | | Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide | | Descriptor: | Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide | | Authors: | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | Deposit date: | 2007-08-21 | | Release date: | 2007-10-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R0V
 | | Structure of the Rsc4 tandem bromodomain acetylated at K25 | | Descriptor: | Chromatin structure-remodeling complex protein RSC4, SULFATE ION | | Authors: | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | Deposit date: | 2007-08-21 | | Release date: | 2007-10-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R10
 | | Structure of an acetylated Rsc4 tandem bromodomain Histone Chimera | | Descriptor: | 1,2-ETHANEDIOL, Chromatin structure-remodeling complex protein RSC4, LINKER, ... | | Authors: | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | Deposit date: | 2007-08-21 | | Release date: | 2007-10-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R0S
 | | Crystal Structure of the Rsc4 tandem bromodomain | | Descriptor: | Chromatin structure-remodeling complex protein RSC4 | | Authors: | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | Deposit date: | 2007-08-21 | | Release date: | 2007-10-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
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2R3C
 | | Structure of the gp41 N-peptide in complex with the HIV entry inhibitor PIE1 | | Descriptor: | CHLORIDE ION, HIV entry inhibitor PIE1, YTTRIUM (III) ION, ... | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-08-29 | | Release date: | 2007-10-02 | | Last modified: | 2018-08-08 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5B
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | Descriptor: | HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-09-03 | | Release date: | 2007-10-02 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R5D
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ... | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-09-03 | | Release date: | 2007-10-02 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2RF3
 | | Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles | | Descriptor: | 5'-d(CGCG(TCY)ATTCGCG)-3', SPERMINE, ZINC ION | | Authors: | Pallan, P.S, Ittig, D, Heroux, A, Wawrzak, Z, Leumann, C.J, Egli, M. | | Deposit date: | 2007-09-27 | | Release date: | 2008-02-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
Chem.Commun.(Camb.), 2008, 2008
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4EQO
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | Deposit date: | 2012-04-19 | | Release date: | 2012-05-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.697 Å) | | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature
To be Published
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4EQN
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23E/I72K at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | Deposit date: | 2012-04-19 | | Release date: | 2012-05-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23E/I72K at cryogenic temperature
To be Published
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4EQP
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS I72D at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | Deposit date: | 2012-04-19 | | Release date: | 2012-05-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS I72D at cryogenic temperature
To be Published
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4GG2
 | | The crystal structure of glutamate-bound human gamma-glutamyltranspeptidase 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | | Deposit date: | 2012-08-04 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
J.Biol.Chem., 288, 2013
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4GDX
 | | Crystal Structure of Human Gamma-Glutamyl Transpeptidase--Glutamate complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | | Deposit date: | 2012-08-01 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
J.Biol.Chem., 288, 2013
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3LX0
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS D21N at cryogenic temperature | | Descriptor: | PHOSPHATE ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Doctrow, B.M, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. | | Deposit date: | 2010-02-24 | | Release date: | 2011-02-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Cooperative Proton Binding in a Cluster of Carboxylic Residues
To be Published
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4POC
 | | Structure of Triosephosphate Isomerase Wild Type human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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4POD
 | | Structure of Triosephosphate Isomerase I170V mutant human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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4R0X
 | | Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5 | | Authors: | LeMaster, D.M, Mustafi, S.M, Brecher, M, Zhang, J, Heroux, A, Li, H.M, Hernandez, G. | | Deposit date: | 2014-08-02 | | Release date: | 2015-05-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
J.Biol.Chem., 290, 2015
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3D0U
 | | Crystal Structure of Lysine Riboswitch Bound to Lysine | | Descriptor: | IRIDIUM HEXAMMINE ION, LYSINE, Lysine Riboswitch RNA | | Authors: | Garst, A.D, Heroux, A, Rambo, R.P, Batey, R.T. | | Deposit date: | 2008-05-02 | | Release date: | 2008-07-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the lysine riboswitch regulatory mRNA element.
J.Biol.Chem., 283, 2008
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3D7J
 | | SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor | | Descriptor: | CHLORIDE ION, SODIUM ION, Uncharacterized protein SCO6650 | | Authors: | Spoonamore, J.E, Roberts, S.A, Heroux, A, Bandarian, V. | | Deposit date: | 2008-05-21 | | Release date: | 2008-10-21 | | Last modified: | 2012-03-28 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor.
Acta Crystallogr.,Sect.F, 64, 2008
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3E66
 | | Crystal structure of the beta-finger domain of yeast Prp8 | | Descriptor: | PRP8 | | Authors: | Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R. | | Deposit date: | 2008-08-14 | | Release date: | 2008-10-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3EIH
 | | Crystal structure of S.cerevisiae Vps4 in the presence of ATPgammaS | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Gonciarz, M.D, Whitby, F.G, Eckert, D.M, Kieffer, C, Heroux, A, Sundquist, W.I, Hill, C.P. | | Deposit date: | 2008-09-15 | | Release date: | 2008-09-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Biochemical and structural studies of yeast vps4 oligomerization.
J.Mol.Biol., 384, 2008
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3EIE
 | | Crystal Structure of S.cerevisiae Vps4 in the SO4-bound state | | Descriptor: | SULFATE ION, Vacuolar protein sorting-associated protein 4 | | Authors: | Gonciarz, M.D, Whitby, F.G, Eckert, D.M, Kieffer, C, Heroux, A, Sundquist, W.I, Hill, C.P. | | Deposit date: | 2008-09-15 | | Release date: | 2008-09-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Biochemical and structural studies of yeast vps4 oligomerization.
J.Mol.Biol., 384, 2008
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3H6M
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS V104E at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Khangulov, V.S, Schlessman, J.L, Heroux, A, Garcia-Moreno, E.B. | | Deposit date: | 2009-04-23 | | Release date: | 2010-03-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V104E at cryogenic temperature
To be Published
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