4GG2

The crystal structure of glutamate-bound human gamma-glutamyltranspeptidase 1

Summary for 4GG2

• Entry DOI: 10.2210/pdb4gg2/pdb
• Related: 4DGX
• Descriptor: Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: ntn-hydrolyase, glutathionine metabolism, n-glycosylation, exterior cell surface, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type II membrane protein: P19440 P19440
• Total number of polymer chains: 2
• Total formula weight: 61228.12

Authors

West, M.B.,Chen, Y.,Wickham, S.,Heroux, A.,Cahill, K.,Hanigan, M.H.,Mooers, B.H.M. (deposition date: 2012-08-04, release date: 2013-09-25, Last modification date: 2023-09-13)

• Primary citation: West, M.B.,Chen, Y.,Wickham, S.,Heroux, A.,Cahill, K.,Hanigan, M.H.,Mooers, B.H.; Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.; J.Biol.Chem., 288:31902-31913, 2013; PubMed: 24047895; DOI: 10.1074/jbc.M113.498139

Experimental method

X-RAY DIFFRACTION (2.21 Å)