2R5D

Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7

Summary for 2R5D

• Entry DOI: 10.2210/pdb2r5d/pdb
• Related: 2R3C 2R5B
• Related PRD ID: PRD_000281
• Descriptor: gp41 N-peptide, HIV entry inhibitor PIE7, GLYCEROL, ... (6 entities in total)
• Functional Keywords: hiv, viral entry, pie, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 22121.19

Authors

VanDemark, A.P.,Welch, B.,Heroux, A.,Hill, C.P.,Kay, M.S. (deposition date: 2007-09-03, release date: 2007-10-02, Last modification date: 2017-10-25)

• Primary citation: Welch, B.D.,Vandemark, A.P.,Heroux, A.,Hill, C.P.,Kay, M.S.; Potent D-peptide inhibitors of HIV-1 entry; Proc.Natl.Acad.Sci.Usa, 104:16828-16833, 2007; PubMed: 17942675; DOI: 10.1073/pnas.0708109104

Experimental method

X-RAY DIFFRACTION (1.66 Å)