2RF3
Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles
Summary for 2RF3
| Entry DOI | 10.2210/pdb2rf3/pdb |
| Descriptor | 5'-d(CGCG(TCY)ATTCGCG)-3', ZINC ION, SPERMINE, ... (4 entities in total) |
| Functional Keywords | dna duplex, x-ray crystal structure, tricyclo-dna, conformationally constrained dna analog, dna |
| Total number of polymer chains | 2 |
| Total formula weight | 7670.63 |
| Authors | Pallan, P.S.,Ittig, D.,Heroux, A.,Wawrzak, Z.,Leumann, C.J.,Egli, M. (deposition date: 2007-09-27, release date: 2008-02-12, Last modification date: 2023-08-30) |
| Primary citation | Pallan, P.S.,Ittig, D.,Heroux, A.,Wawrzak, Z.,Leumann, C.J.,Egli, M. Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles. Chem.Commun.(Camb.), 2008:883-885, 2008 Cited by PubMed Abstract: The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases. PubMed: 18253536DOI: 10.1039/b716390h PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report
