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8C06
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BU of 8c06 by Molmil
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Descriptor: E3 ubiquitin-protein ligase UBR5, ZINC ION
Authors:Hehl, L.A, Prabu, J.R, Schulman, B.A.
Deposit date:2022-12-16
Release date:2023-08-23
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
8C07
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BU of 8c07 by Molmil
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Descriptor: 5-azanylpentan-2-one, E3 ubiquitin-protein ligase UBR5, Polyubiquitin-B
Authors:Hehl, L.A, Prabu, J.R, Schulman, B.A.
Deposit date:2022-12-16
Release date:2023-08-23
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
7NSB
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BU of 7nsb by Molmil
Supramolecular assembly module of yeast Chelator-GID SR4 E3 ubiquitin ligase
Descriptor: Glucose-induced degradation protein 7, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30
Authors:Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS4
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BU of 7ns4 by Molmil
Catalytic module of yeast Chelator-GID SR4 E3 ubiquitin ligase
Descriptor: E3 ubiquitin-protein ligase RMD5, Protein FYV10, ZINC ION
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NSC
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BU of 7nsc by Molmil
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
Descriptor: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS3
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BU of 7ns3 by Molmil
Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate
Descriptor: BJ4_G0018240.mRNA.1.CDS.1, Fructose-bisphosphatase, Glucose-induced degradation protein 8, ...
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS5
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BU of 7ns5 by Molmil
Structure of yeast Fbp1 (Fructose-1,6-bisphosphatase 1)
Descriptor: Fructose-1,6-bisphosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
8PJN
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BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Descriptor: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-23
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8PMQ
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BU of 8pmq by Molmil
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Descriptor: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-29
Release date:2024-01-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
7WUG
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BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
Descriptor: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
Authors:Qiao, S, Cheng, J.D, Schulman, B.A.
Deposit date:2022-02-08
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022

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PDB entries from 2024-11-06

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