8C06
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Summary for 8C06
| Entry DOI | 10.2210/pdb8c06/pdb |
| EMDB information | 16355 16356 16865 16866 16867 |
| Descriptor | E3 ubiquitin-protein ligase UBR5, ZINC ION (2 entities in total) |
| Functional Keywords | e3 ligase, ubr5, ubiquitination, ubq, ubiquitin, hect, ligase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 1861989.58 |
| Authors | Hehl, L.A.,Prabu, J.R.,Schulman, B.A. (deposition date: 2022-12-16, release date: 2023-08-23, Last modification date: 2024-02-14) |
| Primary citation | Hehl, L.A.,Horn-Ghetko, D.,Prabu, J.R.,Vollrath, R.,Vu, D.T.,Perez Berrocal, D.A.,Mulder, M.P.C.,van der Heden van Noort, G.J.,Schulman, B.A. Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5. Nat.Chem.Biol., 20:190-200, 2024 Cited by PubMed: 37620400DOI: 10.1038/s41589-023-01414-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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