8C06

Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E, F...	E3 ubiquitin-protein ligase UBR5	polymer	2806	310266.2	6	UniProt (O95071) Pfam (PF11547) Pfam (PF00658) Pfam (PF00632) In PDB	Homo sapiens (human)	E3 ubiquitin-protein ligase,HECT domain-containing 1,HECT-type E3 ubiquitin transferase UBR5,Hyperplastic discs protein homolog,hHYD,Progestin-induced protein
2	A, D	ZINC ION	non-polymer		65.4	6	Chemie (ZN)

Sequence modifications

A, B, D, E, F, G: 1 - 2799 (UniProt: O95071)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ala -1	-	expression tag
Pro 0	-	expression tag
Arg 503	Lys 503	engineered mutation
Asp 710	Leu 710	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	1861597.1
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	1861989.6

*Water molecules are not included.