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6H3R
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BU of 6h3r by Molmil
Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.
分子名称: DNA (5'-D(P*GP*AP*GP*TP*GP*TP*CP*TP*GP*CP*AP*GP*AP*CP*AP*CP*TP*C)-3'), Mothers against decapentaplegic homolog, ZINC ION
著者Kaczmarska, Z, Marquez, J.A, Macias, M.J.
登録日2018-07-19
公開日2019-09-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-beta signaling
Genes Dev., 2020
5GNU
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BU of 5gnu by Molmil
the structure of mini-MFN1 apo
分子名称: Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J.
登録日2016-07-25
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (4.113 Å)
主引用文献BDLP-like folding of Mitofusin 1
To Be Published
7E3K
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BU of 7e3k by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
分子名称: 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
登録日2021-02-09
公開日2021-09-15
最終更新日2022-03-02
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
7E3L
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BU of 7e3l by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ...
著者Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
登録日2021-02-09
公開日2021-09-15
最終更新日2022-03-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
6JSJ
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BU of 6jsj by Molmil
Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1
分子名称: Dynamin-like GTPase MGM1, mitochondrial, GUANOSINE-5'-DIPHOSPHATE, ...
著者Yan, L, Li, L.
登録日2019-04-08
公開日2020-02-19
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XFU
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BU of 6xfu by Molmil
PmtCD peptide exporter basket domain
分子名称: ABC transporter ATP-binding protein, THIOCYANATE ION
著者Zeytuni, N, Strynadka, N.C.J, Alexander, J.A.N.
登録日2020-06-16
公開日2020-10-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
6EW6
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BU of 6ew6 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
分子名称: B-cell lymphoma 6 protein, ~{N}2-(2-chlorophenyl)-1,3,5-triazine-2,4-diamine
著者Robb, G, Ferguson, A, Hargreaves, D.
登録日2017-11-03
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6EW8
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BU of 6ew8 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
分子名称: B-cell lymphoma 6 protein, CHLORIDE ION, anilinopyrimidine ligand
著者Robb, G, Ferguson, A, Hargreaves, D.
登録日2017-11-03
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6EW7
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BU of 6ew7 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
分子名称: 2-chloranyl-4-[[5-chloranyl-4-[(4-fluorophenyl)amino]pyrimidin-2-yl]amino]benzoic acid, B-cell lymphoma 6 protein, CHLORIDE ION
著者Robb, G, Ferguson, A, Hargreaves, D.
登録日2017-11-03
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6U2D
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BU of 6u2d by Molmil
PmtCD peptide exporter basket domain
分子名称: ABC transporter ATP-binding protein, IODIDE ION, SULFATE ION
著者Zeytuni, N, Strynadka, N.C.J.
登録日2019-08-19
公開日2020-10-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
4DQN
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BU of 4dqn by Molmil
Crystal structure of the branched-chain aminotransferase from Streptococcus mutans
分子名称: Putative branched-chain amino acid aminotransferase IlvE
著者Ruan, J, Li, S.T.
登録日2012-02-16
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of the branched-chain aminotransferase from Streptococcus mutans
Acta Crystallogr.,Sect.D, 68, 2012
4EQ8
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BU of 4eq8 by Molmil
Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Putative uncharacterized protein
著者Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L.
登録日2012-04-18
公開日2012-09-12
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.392 Å)
主引用文献Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4EQA
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BU of 4eqa by Molmil
Crystal structure of PA1844 in complex with PA1845 from Pseudomonas aeruginosa PAO1
分子名称: Putative uncharacterized protein
著者Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L.
登録日2012-04-18
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4F2L
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BU of 4f2l by Molmil
Structure of a regulatory domain of AMPK
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION
著者Xin, F.J, Zhang, Y.Y, Wang, J, Wang, Z.X, Wu, J.W.
登録日2012-05-08
公開日2013-06-26
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conserved regulatory elements in AMPK
Nature, 498, 2013
1Z6H
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BU of 1z6h by Molmil
Solution Structure of Bacillus subtilis BLAP biotinylated-form
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Biotin/Lipoyl Attachment Protein
著者Cui, G, Xia, B.
登録日2005-03-22
公開日2006-03-22
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Identification and solution structures of a single domain biotin/lipoyl attachment protein from Bacillus subtilis
J.Biol.Chem., 281, 2006
6JFK
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BU of 6jfk by Molmil
GDP bound Mitofusin2 (MFN2)
分子名称: CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6JFL
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BU of 6jfl by Molmil
Nucleotide-free Mitofusin2 (MFN2)
分子名称: CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6JFM
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BU of 6jfm by Molmil
Mitofusin2 (MFN2)_T111D
分子名称: ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
4KNR
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BU of 4knr by Molmil
Hin GlmU bound to WG188
分子名称: Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(2-benzyl-7-hydroxy-6-methoxyquinazolin-4-yl)amino]phenyl}benzamide, ...
著者Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A.
登録日2013-05-10
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KPZ
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BU of 4kpz by Molmil
Hin GlmU bound to a small molecule fragment
分子名称: 1-(3-nitrophenyl)dihydropyrimidine-2,4(1H,3H)-dione, Bifunctional protein GlmU, MAGNESIUM ION, ...
著者Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A.
登録日2013-05-14
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
8I1N
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BU of 8i1n by Molmil
Crystal structure of APSK2 domain from human PAPSS2 in complex with endogenous APS and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
著者Zhang, L, Song, W.Y, Zhang, L.
登録日2023-01-13
公開日2023-06-28
最終更新日2023-07-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2.
Structure, 31, 2023
8I1O
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BU of 8i1o by Molmil
Crystal structure of APSK2 domain from human PAPSS2 in complex with exogenous APS and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
著者Zhang, L, Song, W.Y, Zhang, L.
登録日2023-01-13
公開日2023-06-28
最終更新日2023-07-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2.
Structure, 31, 2023
8I1M
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BU of 8i1m by Molmil
Crystal structure of oxidated APSK1 domain from human PAPSS1 in complex with APS and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, PAPSS1 protein, ...
著者Zhang, L, Song, W.Y, Zhang, L.
登録日2023-01-13
公開日2023-06-28
最終更新日2023-07-19
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2.
Structure, 31, 2023
4KNX
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BU of 4knx by Molmil
Hin GlmU Bound to WG176
分子名称: Bifunctional protein GlmU, MAGNESIUM ION, SULFATE ION, ...
著者Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A.
登録日2013-05-10
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KPX
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BU of 4kpx by Molmil
Hin GlmU bound to WG766
分子名称: Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(4-hydroxy-3-nitrobenzoyl)amino]phenyl}pyridine-2-carboxamide, ...
著者Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A.
登録日2013-05-14
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014

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