6H3R
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5GNU
| the structure of mini-MFN1 apo | 分子名称: | Mitofusin-1 | 著者 | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J. | 登録日 | 2016-07-25 | 公開日 | 2016-11-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (4.113 Å) | 主引用文献 | BDLP-like folding of Mitofusin 1 To Be Published
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7E3K
| Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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7E3L
| Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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6JSJ
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6XFU
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6EW6
| Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand | 分子名称: | B-cell lymphoma 6 protein, ~{N}2-(2-chlorophenyl)-1,3,5-triazine-2,4-diamine | 著者 | Robb, G, Ferguson, A, Hargreaves, D. | 登録日 | 2017-11-03 | 公開日 | 2018-10-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6. ACS Chem. Biol., 13, 2018
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6EW8
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6EW7
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6U2D
| PmtCD peptide exporter basket domain | 分子名称: | ABC transporter ATP-binding protein, IODIDE ION, SULFATE ION | 著者 | Zeytuni, N, Strynadka, N.C.J. | 登録日 | 2019-08-19 | 公開日 | 2020-10-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins Sci Adv, 6, 2020
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4DQN
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4EQ8
| Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1 | 分子名称: | GLYCEROL, Putative uncharacterized protein | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | 登録日 | 2012-04-18 | 公開日 | 2012-09-12 | 最終更新日 | 2013-07-24 | 実験手法 | X-RAY DIFFRACTION (1.392 Å) | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem.J., 448, 2012
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4EQA
| Crystal structure of PA1844 in complex with PA1845 from Pseudomonas aeruginosa PAO1 | 分子名称: | Putative uncharacterized protein | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | 登録日 | 2012-04-18 | 公開日 | 2012-09-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem.J., 448, 2012
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4F2L
| Structure of a regulatory domain of AMPK | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION | 著者 | Xin, F.J, Zhang, Y.Y, Wang, J, Wang, Z.X, Wu, J.W. | 登録日 | 2012-05-08 | 公開日 | 2013-06-26 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Conserved regulatory elements in AMPK Nature, 498, 2013
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1Z6H
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6JFK
| GDP bound Mitofusin2 (MFN2) | 分子名称: | CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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6JFL
| Nucleotide-free Mitofusin2 (MFN2) | 分子名称: | CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ... | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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6JFM
| Mitofusin2 (MFN2)_T111D | 分子名称: | ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2 | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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4KNR
| Hin GlmU bound to WG188 | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(2-benzyl-7-hydroxy-6-methoxyquinazolin-4-yl)amino]phenyl}benzamide, ... | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | 登録日 | 2013-05-10 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22, 2014
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4KPZ
| Hin GlmU bound to a small molecule fragment | 分子名称: | 1-(3-nitrophenyl)dihydropyrimidine-2,4(1H,3H)-dione, Bifunctional protein GlmU, MAGNESIUM ION, ... | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | 登録日 | 2013-05-14 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22, 2014
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8I1N
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8I1O
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8I1M
| Crystal structure of oxidated APSK1 domain from human PAPSS1 in complex with APS and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, PAPSS1 protein, ... | 著者 | Zhang, L, Song, W.Y, Zhang, L. | 登録日 | 2023-01-13 | 公開日 | 2023-06-28 | 最終更新日 | 2023-07-19 | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | 主引用文献 | Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. Structure, 31, 2023
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4KNX
| Hin GlmU Bound to WG176 | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, SULFATE ION, ... | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | 登録日 | 2013-05-10 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22, 2014
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4KPX
| Hin GlmU bound to WG766 | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(4-hydroxy-3-nitrobenzoyl)amino]phenyl}pyridine-2-carboxamide, ... | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | 登録日 | 2013-05-14 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22, 2014
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