6H3R

Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.

Summary for 6H3R

• Entry DOI: 10.2210/pdb6h3r/pdb
• Descriptor: Mothers against decapentaplegic homolog, DNA (5'-D(P*GP*AP*GP*TP*GP*TP*CP*TP*GP*CP*AP*GP*AP*CP*AP*CP*TP*C)-3'), ZINC ION, ... (4 entities in total)
• Functional Keywords: smads, transcription factor, dna complex, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 42555.90

Authors

Kaczmarska, Z.,Marquez, J.A.,Macias, M.J. (deposition date: 2018-07-19, release date: 2019-09-18, Last modification date: 2024-01-17)

• Primary citation: Aragon, E.,Wang, Q.,Zou, Y.,Morgani, S.M.,Ruiz, L.,Kaczmarska, Z.,Su, J.,Torner, C.,Tian, L.,Hu, J.,Shu, W.,Agrawal, S.,Gomes, T.,Marquez, J.A.,Hadjantonakis, A.-K.,Macias, M.J.,Massague, J.; Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-beta signaling; Genes Dev., 2020; DOI: 10.1101/gad.330837.119

Experimental method

X-RAY DIFFRACTION (2.75 Å)