8I1N
Crystal structure of APSK2 domain from human PAPSS2 in complex with endogenous APS and ADP
Summary for 8I1N
| Entry DOI | 10.2210/pdb8i1n/pdb |
| Descriptor | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE (3 entities in total) |
| Functional Keywords | adenosine 5'-phosphosulfate kinase domain 2, apsk2, human papss2, biosynthetic protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 89802.09 |
| Authors | Zhang, L.,Song, W.Y.,Zhang, L. (deposition date: 2023-01-13, release date: 2023-06-28, Last modification date: 2023-07-19) |
| Primary citation | Zhang, L.,Song, W.,Li, T.,Mu, Y.,Zhang, P.,Hu, J.,Lin, H.,Zhang, J.,Gao, H.,Zhang, L. Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. Structure, 31:826-835.e3, 2023 Cited by PubMed: 37207644DOI: 10.1016/j.str.2023.04.012 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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