8I1O

Crystal structure of APSK2 domain from human PAPSS2 in complex with exogenous APS and ADP

Summary for 8I1O

• Entry DOI: 10.2210/pdb8i1o/pdb
• Descriptor: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, ... (4 entities in total)
• Functional Keywords: 5'-phosphosulfate kinase 2 domain, apsk2, human papss2, biosynthetic protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 93475.74

Authors

Zhang, L.,Song, W.Y.,Zhang, L. (deposition date: 2023-01-13, release date: 2023-06-28, Last modification date: 2023-07-19)

• Primary citation: Zhang, L.,Song, W.,Li, T.,Mu, Y.,Zhang, P.,Hu, J.,Lin, H.,Zhang, J.,Gao, H.,Zhang, L.; Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2.; Structure, 31:826-835.e3, 2023; PubMed: 37207644; DOI: 10.1016/j.str.2023.04.012

Experimental method

X-RAY DIFFRACTION (2.4 Å)