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5HJN
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BU of 5hjn by Molmil
Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster
分子名称: LD10117p, SULFATE ION
著者Fischer, B, Paesmans, J, Versees, W.
登録日2016-01-13
公開日2016-09-21
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Nat.Struct.Mol.Biol., 23, 2016
5HJQ
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BU of 5hjq by Molmil
Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster in complex with inositol(1,4,5)triphosphate
分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, LD10117p
著者Fischer, B, Paesmans, J, Versees, W.
登録日2016-01-13
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Nat.Struct.Mol.Biol., 23, 2016
4LRS
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BU of 4lrs by Molmil
Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, CHLORIDE ION, ...
著者Fischer, B, Branlant, G, Talfournier, F, Gruez, A.
登録日2013-07-20
公開日2013-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
4LRT
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BU of 4lrt by Molmil
Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, COENZYME A, ...
著者Fischer, B, Branlant, G, Talfournier, F, Gruez, A.
登録日2013-07-20
公開日2013-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
8BE4
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BU of 8be4 by Molmil
Crystal structure of SOS1-KRasG12V-Nanobody14
分子名称: Isoform 2B of GTPase KRas, Nanobody14, Son of sevenless homolog 1
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate
To Be Published
8BE2
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BU of 8be2 by Molmil
Crystal structure of SOS1-Nanobody77
分子名称: Nanobody 77, SULFATE ION, Son of sevenless homolog 1
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.897935 Å)
主引用文献ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate
To Be Published
8BE3
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BU of 8be3 by Molmil
Crystal structure of KRasG12V-Nanobody84
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ...
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate
To Be Published
8BE5
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BU of 8be5 by Molmil
Crystal structure of SOS1-KRasG12V-Nanobody22-Nanobody75
分子名称: Isoform 2B of GTPase KRas, Nanobody22, Nanobody75, ...
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-11-01
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate
To Be Published
6R82
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BU of 6r82 by Molmil
Crystal structure of the TLDc domain of Skywalker/TBC1D24 from Drosophila melanogaster
分子名称: GTPase-activating protein skywalker
著者Fischer, B, Paesmans, J, Versees, W.
登録日2019-03-30
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.046 Å)
主引用文献TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.
Brain, 142, 2019
8BE9
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BU of 8be9 by Molmil
Crystal structure of SOS1-HRas-peptidomimetic5
分子名称: CHLORIDE ION, FORMIC ACID, GTPase HRas, ...
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
8BE6
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BU of 8be6 by Molmil
Crystal structure of SOS1-HRas-peptidomimetic2
分子名称: GTPase HRas, SOS1-HRas-peptidomimetic2, Son of sevenless homolog 1
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.89880252 Å)
主引用文献Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
8BEA
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BU of 8bea by Molmil
Crystal structure of SOS1-HRas-peptidomimetic10
分子名称: GTPase HRas, SOS1-HRas-peptidomimetic10, Son of sevenless homolog 1
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-04-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
8BE7
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BU of 8be7 by Molmil
Crystal structure of SOS1-HRas-peptidomimetic3
分子名称: GTPase HRas, SOS1-HRas-peptidomimetic3, Son of sevenless homolog 1
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
8BE8
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BU of 8be8 by Molmil
Crystal structure of SOS1-HRas-peptidomimetic4
分子名称: FORMIC ACID, GTPase HRas, SOS1-HRas-peptidomimetic4, ...
著者Fischer, B, Wohlkonig, A, Steyaert, J.
登録日2022-10-21
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
6QD6
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BU of 6qd6 by Molmil
Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207
分子名称: CHLORIDE ION, Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207
著者Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkonig, A, Zogg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J.
登録日2018-12-31
公開日2019-12-18
最終更新日2021-01-13
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Nat.Methods, 18, 2021
6XVI
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BU of 6xvi by Molmil
Crystal structure of Megabody Mb-Nb207-c7HopQ_A12
分子名称: Outer membrane protein,Outer membrane protein,Mb-Nb207-c7HopQ_A12
著者Steyaert, J, Uchanski, T, Fischer, B.
登録日2020-01-22
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
6XUX
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BU of 6xux by Molmil
Crystal structure of Megabody Mb-Nb207-cYgjK_NO
分子名称: CALCIUM ION, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody
著者Steyaert, J, Uchanski, T, Fischer, B.
登録日2020-01-21
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.90000641 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
6XV8
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BU of 6xv8 by Molmil
Crystal structure of Megabody Mb-Nb207-c7HopQ_G10
分子名称: Outer membrane protein
著者Steyaert, J, Uchanski, T, Fischer, B.
登録日2020-01-21
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
6QFA
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BU of 6qfa by Molmil
CryoEM structure of a beta3K279T GABA(A)R homomer in complex with histamine and megabody Mb25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit beta-3, HISTAMINE, ...
著者Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkoening, A, Zoegg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J.
登録日2019-01-09
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
7QLF
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BU of 7qlf by Molmil
Conformational ensemble of solnatide in solution
分子名称: Tumor necrosis factor
著者Macias, M.J, Martin-Malpartida, P.
登録日2021-12-20
公開日2022-06-08
実験手法SOLUTION NMR
主引用文献Conformational ensemble of the TNF-derived peptide solnatide in solution.
Comput Struct Biotechnol J, 20, 2022

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件を2024-04-24に公開中

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