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8BE2

Crystal structure of SOS1-Nanobody77

Summary for 8BE2
Entry DOI10.2210/pdb8be2/pdb
DescriptorSon of sevenless homolog 1, Nanobody 77, SULFATE ION, ... (4 entities in total)
Functional Keywordscomplex, stabilizer, signaling protein
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight73793.56
Authors
Fischer, B.,Wohlkonig, A.,Steyaert, J. (deposition date: 2022-10-21, release date: 2023-11-01)
Primary citationFischer, B.,Wohlkonig, A.,Steyaert, J.
ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.89793505929 Å)
Structure validation

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