8BE9
Crystal structure of SOS1-HRas-peptidomimetic5
Summary for 8BE9
Entry DOI | 10.2210/pdb8be9/pdb |
Descriptor | GTPase HRas, Son of sevenless homolog 1, SOS1-HRas-peptidomimetic5, ... (6 entities in total) |
Functional Keywords | complex, stabilizer, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 82290.37 |
Authors | Fischer, B.,Wohlkonig, A.,Steyaert, J. (deposition date: 2022-10-21, release date: 2023-04-26, Last modification date: 2024-02-07) |
Primary citation | Van Holsbeeck, K.,Fischer, B.,Gonzalez, S.,Gadais, C.,Versees, W.,Martins, J.C.,Martin, C.,Wohlkonig, A.,Steyaert, J.,Ballet, S. Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS. Angew.Chem.Int.Ed.Engl., 62:e202219095-e202219095, 2023 Cited by PubMed: 37067463DOI: 10.1002/anie.202219095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
Download full validation report