8BE3

Crystal structure of KRasG12V-Nanobody84

This is a non-PDB format compatible entry.

Summary for 8BE3

• Entry DOI: 10.2210/pdb8be3/pdb
• Descriptor: Nanobody84, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: complex, stabilizer, signaling protein
• Biological source: Lama glama; More
• Total number of polymer chains: 4
• Total formula weight: 71323.75

Authors

Fischer, B.,Wohlkonig, A.,Steyaert, J. (deposition date: 2022-10-21, release date: 2023-11-01, Last modification date: 2024-08-14)

• Primary citation: Fischer, B.,Uchanski, T.,Sheryazdanova, A.,Gonzalez, S.,Volkov, A.N.,Brosens, E.,Zogg, T.,Kalichuk, V.,Ballet, S.,Versees, W.,Sablina, A.A.,Pardon, E.,Wohlkonig, A.,Steyaert, J.; Allosteric nanobodies to study the interactions between SOS1 and RAS.; Nat Commun, 15:6214-6214, 2024; PubMed: 39043660; DOI: 10.1038/s41467-024-50349-2

Experimental method

X-RAY DIFFRACTION (1.85 Å)