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3FJN
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BU of 3fjn by Molmil
The crystal structure of 17-alpha hydroxysteroid dehydrogenase Y224D mutant.
Descriptor: ACETATE ION, Aldo-keto reductase family 1 member C21
Authors:Dhagat, U, El-Kabbani, O.
Deposit date:2008-12-14
Release date:2009-11-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme
Acta Crystallogr.,Sect.D, 66, 2010
2O4U
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BU of 2o4u by Molmil
Crystal structure of Mammalian Dimeric Dihydrodiol Dehydrogenase
Descriptor: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, GLYCEROL, ...
Authors:Carbone, V, El-Kabbani, O.
Deposit date:2006-12-04
Release date:2007-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: probing the subunit interface with site-directed mutagenesis.
Proteins, 70, 2008
2O48
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BU of 2o48 by Molmil
Crystal structure of Mammalian Dimeric Dihydrodiol Dehydrogenase
Descriptor: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, P-HYDROXYACETOPHENONE, ...
Authors:Carbone, V, El-Kabbani, O.
Deposit date:2006-12-04
Release date:2007-07-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: probing the subunit interface with site-directed mutagenesis.
Proteins, 70, 2008
2PZN
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BU of 2pzn by Molmil
The crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinant
Descriptor: (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ruiz, F, Hazemann, I, Darmanin, C, Mitschler, A, Van Zandt, M, Joachimiak, A, El-Kabbani, O, Podjarny, A.
Deposit date:2007-05-18
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:The Crystallographic Structure of Alr2-Idd393 Complex Confirms Leu300 as a Specificity Determinant
To be Published
2POQ
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BU of 2poq by Molmil
Dimeric Dihydrodiol Dehydrogenase complexed with inhibitor, Isoascorbic acid
Descriptor: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, ISOASCORBIC ACID, ...
Authors:Carbone, V, El-Kabbani, O.
Deposit date:2007-04-27
Release date:2007-07-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid.
Acta Crystallogr.,Sect.D, 64, 2008
1BIO
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BU of 1bio by Molmil
HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR
Descriptor: COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE
Authors:Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
1C3I
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BU of 1c3i by Molmil
HUMAN STROMELYSIN-1 CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
Descriptor: 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER, CALCIUM ION, STROMELYSIN-1, ...
Authors:Steele, D.L, Kammlott, R.U, Crowther, R.L, Birktoft, J.J, Dunten, P, Engler, J.E.
Deposit date:1999-07-27
Release date:2000-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.
Protein Eng., 13, 2000
1DSU
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BU of 1dsu by Molmil
HUMAN FACTOR D, COMPLEMENT ACTIVATING ENZYME
Descriptor: FACTOR D
Authors:Narayana, S.V.L, Volanakis, J.E, Delucas, L.J.
Deposit date:1995-09-15
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human factor D. A complement system protein at 2.0 A resolution.
J.Mol.Biol., 235, 1994
1HFD
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BU of 1hfd by Molmil
HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM
Descriptor: COMPLEMENT FACTOR D
Authors:Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
2RCR
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BU of 2rcr by Molmil
STRUCTURE OF THE MEMBRANE-BOUND PROTEIN PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, Coenzyme Q10, ...
Authors:Chang, C.-H, Norris, J, Schiffer, M.
Deposit date:1991-02-04
Release date:1993-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the membrane-bound protein photosynthetic reaction center from Rhodobacter sphaeroides.
Biochemistry, 30, 1991
1DST
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BU of 1dst by Molmil
MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY
Descriptor: FACTOR D
Authors:Narayana, S.V.L, Volanakis, J.E.
Deposit date:1995-09-13
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
J.Biol.Chem., 270, 1995
2OKK
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BU of 2okk by Molmil
The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65)
Descriptor: GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
2OKJ
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BU of 2okj by Molmil
The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)
Descriptor: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
1FDP
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BU of 1fdp by Molmil
PROENZYME OF HUMAN COMPLEMENT FACTOR D, RECOMBINANT PROFACTOR D
Descriptor: PROENZYME OF COMPLEMENT FACTOR D
Authors:Jing, H, Macon, K.J, Moore, D, Delucas, L.J, Volanakis, J.E, Narayana, S.V.L.
Deposit date:1998-12-03
Release date:1999-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D.
Embo J., 18, 1999
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