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4F6N
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BU of 4f6n by Molmil
Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F6M
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BU of 4f6m by Molmil
Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H6J
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BU of 4h6j by Molmil
Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
分子名称: ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA
著者Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A.
登録日2012-09-19
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
1XJH
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BU of 1xjh by Molmil
NMR structure of the redox switch domain of the E. coli Hsp33
分子名称: 33 kDa chaperonin, ZINC ION
著者Won, H.S, Low, L.Y, De Guzman, R.N, Martinez-Yamout, M.A, Jakob, U, Dyson, H.J.
登録日2004-09-23
公開日2004-10-05
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The Zinc-dependent Redox Switch Domain of the Chaperone Hsp33 has a Novel Fold
J.Mol.Biol., 341, 2004
1ZU1
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BU of 1zu1 by Molmil
Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
分子名称: RNA binding protein ZFa, ZINC ION
著者Moller, H.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2005-05-29
公開日2005-09-20
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa
J.Mol.Biol., 351, 2005
2AVX
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BU of 2avx by Molmil
solution structure of E coli SdiA1-171
分子名称: N-(2-OXOTETRAHYDROFURAN-3-YL)OCTANAMIDE, Regulatory protein sdiA
著者Yao, Y, Martinez-Yamout, M.A, Dickerson, T.J, Brogan, A.P, Wright, P.E, Dyson, H.J.
登録日2005-08-30
公開日2006-06-20
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones.
J.Mol.Biol., 355, 2006
2AGH
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BU of 2agh by Molmil
Structural basis for cooperative transcription factor binding to the CBP coactivator
分子名称: Crebbp protein, Myb proto-oncogene protein, Zinc finger protein HRX
著者De Guzman, R.N, Goto, N.K, Dyson, H.J, Wright, P.E.
登録日2005-07-26
公開日2005-11-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
J.Mol.Biol., 355, 2006
2JP9
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BU of 2jp9 by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-04-30
公開日2007-10-30
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2JPA
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BU of 2jpa by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(P*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DG)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-01
公開日2007-10-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2KA4
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BU of 2ka4 by Molmil
NMR structure of the CBP-TAZ1/STAT2-TAD complex
分子名称: Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION
著者Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2008-10-30
公開日2009-04-21
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
Embo J., 28, 2009
2KA6
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BU of 2ka6 by Molmil
NMR structure of the CBP-TAZ2/STAT1-TAD complex
分子名称: CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION
著者Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2008-10-30
公開日2009-04-07
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.
Embo J., 28, 2009
2L14
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BU of 2l14 by Molmil
Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
分子名称: CREB-binding protein, Cellular tumor antigen p53
著者Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2010-07-22
公開日2010-11-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
2M9F
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BU of 2m9f by Molmil
NMR solution structure of Pin1 WW domain mutant 5-1g
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-07
公開日2013-06-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9E
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BU of 2m9e by Molmil
NMR solution structure of Pin1 WW domain mutant 5-1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-07
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9J
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BU of 2m9j by Molmil
NMR solution structure of Pin1 WW domain mutant 6-1g
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-10
公開日2013-06-26
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9I
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BU of 2m9i by Molmil
NMR solution structure of Pin1 WW domain variant 6-1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-10
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
分子名称: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ED1
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BU of 8ed1 by Molmil
Bovine Fab 5C1
分子名称: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECQ
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BU of 8ecq by Molmil
Bovine Fab 2G3
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EDF
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BU of 8edf by Molmil
Bovine Fab SKD in complex with Sars COV-2 receptor binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKD Fab Light chain, SKD Fab heavy chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECV
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BU of 8ecv by Molmil
Bovine Fab 2F12
分子名称: 2F12 Fab Heavy chain, 2F12 Fab Light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
5CC9
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BU of 5cc9 by Molmil
L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E.
登録日2015-07-01
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
5CCC
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BU of 5ccc by Molmil
wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E.
登録日2015-07-01
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
8W1N
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BU of 8w1n by Molmil
Structure of transthyretin pathogenic mutation A120S
分子名称: Transthyretin
著者Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-16
公開日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
8W2W
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BU of 8w2w by Molmil
Structure of transthyretin synthetic mutation A120L
分子名称: Transthyretin
著者Yang, K, Sun, X, Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-21
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published

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件を2024-05-15に公開中

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