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5IZS
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BU of 5izs by Molmil
De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
Descriptor: Designed protein 5L6HC3_1
Authors:Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Oberdorfer, G.
Deposit date:2016-03-25
Release date:2016-05-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
5JQE
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BU of 5jqe by Molmil
Crystal structure of caspase8 tDED
Descriptor: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T, Li, Y, Lu, A, Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
6O35
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BU of 6o35 by Molmil
Crystal structure of a de novo designed octameric helical-bundle protein
Descriptor: de novo designed WSHC8
Authors:Bick, M.J, Xu, C, Sankaran, B, Baker, D.
Deposit date:2019-02-25
Release date:2020-03-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational design of transmembrane pores.
Nature, 585, 2020
7AIP
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BU of 7aip by Molmil
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Reference Map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Liko, I, Tehan, B.G, Almeida, F.G, Elkins, J, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC)
Deposit date:2020-09-28
Release date:2021-06-02
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Embo J., 40, 2021
7AIR
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BU of 7air by Molmil
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Liko, I, Tehan, B.G, Almeida, F.G, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC)
Deposit date:2020-09-28
Release date:2021-06-02
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Embo J., 40, 2021
7AIQ
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BU of 7aiq by Molmil
Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 4, ...
Authors:Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Liko, I, Tehan, B.G, Almeida, F.G, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC)
Deposit date:2020-09-28
Release date:2021-06-02
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Embo J., 40, 2021
6O6C
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BU of 6o6c by Molmil
RNA polymerase II elongation complex arrested at a CPD lesion
Descriptor: DNA (27-MER), DNA (5'-D(P*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*CP*AP*GP*AP*GP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Lahiri, I, Leshziner, A.E.
Deposit date:2019-03-05
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:3.1 angstrom structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids.
J.Struct.Biol., 207, 2019
6P4X
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BU of 6p4x by Molmil
Crystal Structure of the S. cerevisiae glucokinase, Glk1
Descriptor: Glucokinase-1, PHOSPHATE ION
Authors:Stoddard, P.R, Garner, E.C, Murray, A.W.
Deposit date:2019-05-28
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Polymerization in the actin ATPase clan regulates hexokinase activity in yeast.
Science, 367, 2020
6PDT
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BU of 6pdt by Molmil
cryoEM structure of yeast glucokinase filament
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glucokinase-1, MAGNESIUM ION, ...
Authors:Lynch, E.M, Dosey, A.M, Farrell, D.P, Stoddard, P.R, Kollman, J.M.
Deposit date:2019-06-19
Release date:2020-03-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polymerization in the actin ATPase clan regulates hexokinase activity in yeast.
Science, 367, 2020
6BAA
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BU of 6baa by Molmil
Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Martin, G.M, Yoshioka, C, Shyng, S.L.
Deposit date:2017-10-12
Release date:2017-11-01
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.
Elife, 6, 2017
6CVN
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BU of 6cvn by Molmil
Model of synthetic tau (R2x4) bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nogales, E, Kellogg, E.H.
Deposit date:2018-03-28
Release date:2018-05-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
6CVJ
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BU of 6cvj by Molmil
Model of synthetic tau (four tandem repeats of first repeat sequence) bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nogales, E, Kellogg, E.H.
Deposit date:2018-03-28
Release date:2018-05-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
8D06
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BU of 8d06 by Molmil
Hallucinated C3 protein assembly HALC3_104
Descriptor: HALC3_104
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D09
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BU of 8d09 by Molmil
Hallucinated C4 protein assembly HALC4_136
Descriptor: HALC4_136
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D08
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BU of 8d08 by Molmil
Hallucinated C4 protein assembly HALC4_135
Descriptor: HALC4_135
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D04
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BU of 8d04 by Molmil
Hallucinated C2 protein assembly HALC2_062
Descriptor: HALC2_062
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D07
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BU of 8d07 by Molmil
Hallucinated C3 protein assembly HALC3_109
Descriptor: HALC3_109
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D03
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BU of 8d03 by Molmil
Hallucinated C2 protein assembly HALC2_068
Descriptor: HALC2_068
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D05
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BU of 8d05 by Molmil
Hallucinated C2 protein assembly HALC2_065
Descriptor: HALC2_065
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8DT0
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BU of 8dt0 by Molmil
Scaffolding protein functional sites using deep learning
Descriptor: Scaffolding protein functional sites
Authors:Bera, A.K, Watson, J, Baker, D.
Deposit date:2022-07-24
Release date:2022-08-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Scaffolding protein functional sites using deep learning.
Science, 377, 2022
7KUW
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BU of 7kuw by Molmil
High-throughput design and refinement of stable proteins using sequence-only models
Descriptor: Sequence-Based Designed Protein nmt_0994_guided_02
Authors:Bera, A.K, Stewart, L, Kang, A.S, Baker, D.
Deposit date:2020-11-25
Release date:2021-12-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Large-scale design and refinement of stable proteins using sequence-only models.
Plos One, 17, 2022
7M5T
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BU of 7m5t by Molmil
Solution NMR structure of de novo designed protein 0515
Descriptor: De novo designed protein 0515
Authors:Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T.
Deposit date:2021-03-24
Release date:2021-12-15
Last modified:2022-07-27
Method:SOLUTION NMR
Cite:De novo protein design by deep network hallucination.
Nature, 600, 2021
5V7V
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BU of 5v7v by Molmil
Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M.
Deposit date:2017-03-20
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
5V6P
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BU of 5v6p by Molmil
CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1
Descriptor: ERAD-associated E3 ubiquitin-protein ligase HRD1
Authors:Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M.
Deposit date:2017-03-17
Release date:2017-08-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
6TMS
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BU of 6tms by Molmil
Crystal structure of a de novo designed hexameric helical-bundle protein
Descriptor: SULFATE ION, a novel designed pore protein, affinity purification tag
Authors:Xu, C, Pei, X.Y, Luisi, B.F, Baker, D.
Deposit date:2019-12-05
Release date:2020-04-29
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational design of transmembrane pores.
Nature, 585, 2020

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