7KUW

High-throughput design and refinement of stable proteins using sequence-only models

Summary for 7KUW

Entry DOI	10.2210/pdb7kuw/pdb
Descriptor	Sequence-Based Designed Protein nmt_0994_guided_02 (1 entity in total)
Functional Keywords	de novo designed, neural network, evaluator model, deep network hallucination, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	7193.41
Authors	Bera, A.K.,Stewart, L.,Kang, A.S.,Baker, D. (deposition date: 2020-11-25, release date: 2021-12-15, Last modification date: 2024-04-03)
Primary citation	Singer, J.M.,Novotney, S.,Strickland, D.,Haddox, H.K.,Leiby, N.,Rocklin, G.J.,Chow, C.M.,Roy, A.,Bera, A.K.,Motta, F.C.,Cao, L.,Strauch, E.M.,Chidyausiku, T.M.,Ford, A.,Ho, E.,Zaitzeff, A.,Mackenzie, C.O.,Eramian, H.,DiMaio, F.,Grigoryan, G.,Vaughn, M.,Stewart, L.J.,Baker, D.,Klavins, E. Large-scale design and refinement of stable proteins using sequence-only models. Plos One, 17:e0265020-e0265020, 2022 Cited by PubMed: 35286324 DOI: 10.1371/journal.pone.0265020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.43 Å)

Structure validation