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4D5E
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BU of 4d5e by Molmil
Crystal Structure of recombinant wildtype CDH
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Loschonsky, S, Wacker, T, Waltzer, S, Giovannini, P.P, McLeish, M.J, Andrade, S.L.A, Mueller, M.
Deposit date:2014-11-03
Release date:2015-01-21
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Extended Reaction Scope of Thiamine Diphosphate Dependent Cyclohexane-1,2-Dione Hydrolase: From C-C Bond Cleavage to C-C Bond Ligation.
Angew.Chem.Int.Ed.Engl., 53, 2014
3ZGZ
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BU of 3zgz by Molmil
Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and toxic moiety from agrocin 84 (TM84) in aminoacylation-like conformation
Descriptor: LEUCINE--TRNA LIGASE, MAGNESIUM ION, TRNA-LEU UAA ISOACCEPTOR, ...
Authors:Chopra, S, Palencia, A, Virus, C, Tripathy, A, Temple, B.R, Velazquez-Campoy, A, Cusack, S, Reader, J.S.
Deposit date:2012-12-19
Release date:2013-01-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Plant Tumour Biocontrol Agent Employs a tRNA-Dependent Mechanism to Inhibit Leucyl-tRNA Synthetase
Nat.Commun., 4, 2013
1MHW
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BU of 1mhw by Molmil
Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
Descriptor: 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L
Authors:Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O.
Deposit date:2002-08-21
Release date:2002-12-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
3W5K
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BU of 3w5k by Molmil
Crystal structure of Snail1 and importin beta complex
Descriptor: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1
Authors:Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J.
Deposit date:2013-01-30
Release date:2014-03-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
Acta Crystallogr.,Sect.D, 70, 2014
3TNF
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BU of 3tnf by Molmil
LidA from Legionella in complex with active Rab8a
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, LidA, MAGNESIUM ION, ...
Authors:Schoebel, S, Cichy, A.L, Goody, R.S, Itzen, A.
Deposit date:2011-09-01
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protein LidA from Legionella is a Rab GTPase supereffector.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RMR
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BU of 3rmr by Molmil
Crystal structure of Hyaloperonospora arabidopsidis ATR1 effector domain
Descriptor: Avirulence protein
Authors:Chou, S, Krasileva, K.V, Holton, J.M, Staskawicz, B.J, Alber, T.
Deposit date:2011-04-21
Release date:2011-07-20
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Hyaloperonospora arabidopsidis ATR1 effector has distributed recognition surfaces and a structural subdomain conserved across oomycete species
To be Published
3JZA
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BU of 3jza by Molmil
Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila
Descriptor: PHOSPHATE ION, Ras-related protein Rab-1B, Uncharacterized protein DrrA
Authors:Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A.
Deposit date:2009-09-23
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
Mol.Cell, 36, 2009
3JZ9
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BU of 3jz9 by Molmil
Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila
Descriptor: Uncharacterized protein DrrA
Authors:Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A.
Deposit date:2009-09-23
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
Mol.Cell, 36, 2009
3CAD
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BU of 3cad by Molmil
Crystal structure of Natural Killer Cell Receptor, Ly49G
Descriptor: Lectin-related NK cell receptor LY49G1
Authors:Cho, S.
Deposit date:2008-02-19
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors.
J.Biol.Chem., 283, 2008
5F5B
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BU of 5f5b by Molmil
Structure of E.Coli GlpG complexed with peptidic inhibitor Ac-VRMA-CHO
Descriptor: Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
Authors:Urban, S, Cho, S, Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5G
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BU of 5f5g by Molmil
Structure of E.Coli GlpG Y205F mutant complexed with peptidic inhibitor Ac-RMA-CHO in the DMPC/CHAPSO bicelle
Descriptor: ACE-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
Authors:Urban, S, Cho, S, Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-04-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
6PJU
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BU of 6pju by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJR
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BU of 6pjr by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJA
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BU of 6pja by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ5
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BU of 6pj5 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-27
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ9
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BU of 6pj9 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ7
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BU of 6pj7 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJQ
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BU of 6pjq by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ8
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BU of 6pj8 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJP
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BU of 6pjp by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-28
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ4
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BU of 6pj4 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor: Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:Urban, S, Cho, S.
Deposit date:2019-06-27
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
5F5J
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BU of 5f5j by Molmil
E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
Descriptor: Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
Authors:Urban, S, Cho, S, Dickey, S.
Deposit date:2015-12-04
Release date:2016-02-10
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5K
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BU of 5f5k by Molmil
E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
Descriptor: Peptidic derivative of Gurken: ACE-ARG-LYS-VAL-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
Authors:Urban, S, Cho, S, Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-10
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5D
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BU of 5f5d by Molmil
Crystal structures and Inhibition kinetics reveal a two-state catalytic mechanism with drug design implications for rhomboid proteolysis
Descriptor: Rhomboid protease GlpG
Authors:Urban, S, Cho, S, Dickey, S.W.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
3G8K
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BU of 3g8k by Molmil
Crystal structure of murine natural killer cell receptor, Ly49L4
Descriptor: Lectin-related NK cell receptor LY49L1
Authors:Cho, S.
Deposit date:2009-02-12
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
Immunity, 31, 2009

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