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SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOC

SARS-CoV-2 S RBD B.1.617.1 kappa variant S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, S309 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOD

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

6V67

Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2
Descriptor:	PD-1 Binding Miniprotein GR918.2
Authors:	Bick, M.J, Bryan, C.M, Baker, D, Dimaio, F, Kang, A.
Deposit date:	2019-12-04
Release date:	2020-12-09
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.07 Å)
Cite:	Computational design of a synthetic PD-1 agonist. Proc.Natl.Acad.Sci.USA, 118, 2021

7M0Q

Crystal structure of deep network hallucinated protein 0738_mod
Descriptor:	Network hallucinated protein 0738_mod
Authors:	Pellock, S.J, Bera, A.K, Anishchenko, I, Baker, D.
Deposit date:	2021-03-11
Release date:	2021-12-29
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	De novo protein design by deep network hallucination. Nature, 600, 2021

8EOV

Precisely patterned nanofibers made from extendable protein multiplexes
Descriptor:	C2HR1_4r, PHOSPHATE ION
Authors:	Bera, A.K, Bethel, N.P.
Deposit date:	2022-10-04
Release date:	2023-08-16
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8ERW

Precisely patterned nanofibers made from extendable protein multiplexes
Descriptor:	C2HR4_8r
Authors:	Bick, M.J, Parmeggiani, F, Bethel, N.P, Sankaran, B, Baker, D.
Deposit date:	2022-10-12
Release date:	2023-08-23
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.88 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8EOX

Precisely patterned nanofibers made from extendable protein multiplexes
Descriptor:	C4HR1_4r
Authors:	Bera, A.K, Bethel, N.P.
Deposit date:	2022-10-04
Release date:	2023-08-16
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (3.3 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8EOZ

Precisely patterned nanofibers made from extendable protein multiplexes
Descriptor:	C3HR3_4r
Authors:	Bera, A.K, Bethel, N.P, Kang, A.
Deposit date:	2022-10-04
Release date:	2023-08-16
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8FBI

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_39
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Method:	X-RAY DIFFRACTION (3.61 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FBJ

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_60
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Method:	X-RAY DIFFRACTION (3.25 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FBN

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_73
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Method:	X-RAY DIFFRACTION (3.04 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FBO

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_102
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Method:	X-RAY DIFFRACTION (3.4 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FBK

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_65
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Method:	X-RAY DIFFRACTION (3.15 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8G8I

C3HR3_9r_shift4: Extendable repeat protein fiber
Descriptor:	C3HR3_9r_shift4
Authors:	Bethel, N.P, Borst, A.J.
Deposit date:	2023-02-17
Release date:	2023-08-30
Last modified:	2023-12-13
Method:	ELECTRON MICROSCOPY (3.92 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8GAA

C6HR1_4r: Extendable repeat protein hexamer
Descriptor:	C6HR1_4r
Authors:	Bethel, N.P, Borst, A.J, Baker, D.
Deposit date:	2023-02-22
Release date:	2023-08-30
Last modified:	2023-12-20
Method:	ELECTRON MICROSCOPY (4.24 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8GA9

C4HR1_4r: Extendable repeat protein tetramer
Descriptor:	C4HR1_4r
Authors:	Bethel, N.P, Borst, A.J.
Deposit date:	2023-02-22
Release date:	2023-08-30
Last modified:	2023-12-20
Method:	ELECTRON MICROSCOPY (3.71 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8GAQ

C5HR2_4r: Extendable repeat protein pentamer
Descriptor:	C5HR2_4r
Authors:	Bethel, N.P, Borst, A.J.
Deposit date:	2023-02-23
Release date:	2023-08-30
Last modified:	2023-12-20
Method:	ELECTRON MICROSCOPY (3.73 Å)
Cite:	Precisely patterned nanofibres made from extendable protein multiplexes. Nat.Chem., 15, 2023

8GL3

De novo design of monomeric helical bundles for pH-controlled membrane lysis
Descriptor:	pRLB-519
Authors:	Goldbach, N, Bera, A.K, Baker, D, Kang, A.
Deposit date:	2023-03-20
Release date:	2023-09-06
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	De novo design of monomeric helical bundles for pH-controlled membrane lysis. Protein Sci., 32, 2023

8UR7

I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-10-25
Release date:	2023-12-27
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023

8UR5

I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-10-25
Release date:	2023-12-27
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023

6DG5

Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ...
Authors:	Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C.
Deposit date:	2018-05-16
Release date:	2019-01-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.516 Å)
Cite:	De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019

6DG6

Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic
Descriptor:	Neoleukin-2/15
Authors:	Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C.
Deposit date:	2018-05-16
Release date:	2019-01-16
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.999 Å)
Cite:	De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019

7KNA

Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5
Authors:	Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-11-04
Release date:	2021-03-31
Last modified:	2021-05-05
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature, 592, 2021

2X5F

Crystal structure of the methicillin-resistant Staphylococcus aureus Sar2028, an aspartate_tyrosine_phenylalanine pyridoxal-5'-phosphate dependent aminotransferase
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASPARTATE_TYROSINE_PHENYLALANINE PYRIDOXAL-5' PHOSPHATE-DEPENDENT AMINOTRANSFERASE, MAGNESIUM ION, ...
Authors:	Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
Deposit date:	2010-02-08
Release date:	2010-07-21
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genom., 11, 2010

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