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8UR5

I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)

Summary for 8UR5
Entry DOI10.2210/pdb8ur5/pdb
EMDB information42482
DescriptorTrimer head HA,Hemagglutinin HA1 chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywordsinfluenza virus, hemagglutinin nanoparticle vaccine, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
Biological sourcesynthetic construct
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Total number of polymer chains3
Total formula weight135415.11
Authors
Park, Y.J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2023-10-25, release date: 2023-12-27)
Primary citationEllis, D.,Dosey, A.,Boyoglu-Barnum, S.,Park, Y.J.,Gillespie, R.,Syeda, H.,Hutchinson, G.B.,Tsybovsky, Y.,Murphy, M.,Pettie, D.,Matheson, N.,Chan, S.,Ueda, G.,Fallas, J.A.,Carter, L.,Graham, B.S.,Veesler, D.,Kanekiyo, M.,King, N.P.
Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42:113552-113552, 2023
Cited by
PubMed: 38096058
DOI: 10.1016/j.celrep.2023.113552
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

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