8FBK

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains

Summary for 8FBK

• Entry DOI: 10.2210/pdb8fbk/pdb
• Descriptor: KWOCA_65 (1 entity in total)
• Functional Keywords: designed protein, protein assemblies, negative design, cryptic transmembrane domains, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 28111.40

Authors

Wang, J.Y.,Khmelinskaia, A.,Bera, A.K.,King, N.P. (deposition date: 2022-11-29, release date: 2023-03-22)

• Primary citation: Wang, J.Y.J.,Khmelinskaia, A.,Sheffler, W.,Miranda, M.C.,Antanasijevic, A.,Borst, A.J.,Torres, S.V.,Shu, C.,Hsia, Y.,Nattermann, U.,Ellis, D.,Walkey, C.,Ahlrichs, M.,Chan, S.,Kang, A.,Nguyen, H.,Sydeman, C.,Sankaran, B.,Wu, M.,Bera, A.K.,Carter, L.,Fiala, B.,Murphy, M.,Baker, D.,Ward, A.B.,King, N.P.; Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.; Proc.Natl.Acad.Sci.USA, 120:e2214556120-e2214556120, 2023; PubMed: 36888664; DOI: 10.1073/pnas.2214556120

Experimental method

X-RAY DIFFRACTION (3.15 Å)