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6Q8J
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BU of 6q8j by Molmil
Nterminal domain of human SMU1 in complex with LSP641
Descriptor: 1-~{tert}-butyl-3-[6-(3,5-dimethoxyphenyl)-2-[[1-[1-(phenylmethyl)piperidin-4-yl]-1,2,3-triazol-4-yl]methylamino]pyrido[2,3-d]pyrimidin-7-yl]urea, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2025-10-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q8I
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BU of 6q8i by Molmil
Nterminal domain of human SMU1 in complex with human REDmid
Descriptor: Protein Red, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q8F
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BU of 6q8f by Molmil
Nterminal domain of human SMU1
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, WD40 repeat-containing protein SMU1
Authors:Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
9FTS
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BU of 9fts by Molmil
Serial microseconds crystallography at ID29 using SACLA extruder: Thaumatin
Descriptor: L(+)-TARTARIC ACID, Thaumatin I
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FTX
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BU of 9ftx by Molmil
Serial microseconds crystallography at ID29 using fixed-target (small foils): Proteinase K with 10 um spacing between X-ray pulses
Descriptor: CALCIUM ION, NITRATE ION, Proteinase K
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FTU
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BU of 9ftu by Molmil
Serial microseconds crystallography at ID29 using ASU extruder: Thaumatin
Descriptor: L(+)-TARTARIC ACID, Thaumatin I
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FTY
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BU of 9fty by Molmil
Serial microseconds crystallography at ID29 using fixed-target (small foils): Proteinase K with 20 um spacing between X-ray pulses
Descriptor: CALCIUM ION, NITRATE ION, Proteinase K
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FUE
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BU of 9fue by Molmil
Serial microseconds crystallography at ID29 using fixed-target (Si Chip): Lysozyme - with ligand GlcNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, Lysozyme C, ...
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-26
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FTV
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BU of 9ftv by Molmil
Serial microseconds crystallography at ID29 using MPI extruder: Thaumatin
Descriptor: L(+)-TARTARIC ACID, Thaumatin I
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FUP
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BU of 9fup by Molmil
Serial microseconds crystallography at ID29 using fixed-target (small foils): A2a adenosine receptor co-crystallised with Istradefylline
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione, ...
Authors:Orlans, J, Rose, S.L, Ferguson, G, Lebon, G, Basu, S, de Sanctis, D.
Deposit date:2024-06-26
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FUD
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BU of 9fud by Molmil
Serial microseconds crystallography at ID29 using fixed-target (Si Chip): Lysozyme - without ligand GlcNAc (apo)
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-26
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
9FU1
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BU of 9fu1 by Molmil
Serial microseconds crystallography at ID29 using fixed-target (large foils): Proteinase K with 50 um spacing between X-ray pulses
Descriptor: CALCIUM ION, NITRATE ION, Proteinase K
Authors:Orlans, J, Rose, S.L, Basu, S, de Sanctis, D.
Deposit date:2024-06-25
Release date:2025-01-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.
Commun Chem, 8, 2025
8RI7
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BU of 8ri7 by Molmil
Beta-galactosidase (LacZ) in complex with glycosyrin from Pseudomonas syringae.
Descriptor: (2S,3R,4S)-2-[bis(oxidanyl)methyl]pyrrolidine-3,4-diol, Beta-galactosidase, MAGNESIUM ION, ...
Authors:Hardenbrook, N.J, Sheng, Y, Zhang, P.
Deposit date:2023-12-18
Release date:2025-01-01
Last modified:2026-04-01
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology.
Science, 388, 2025
8RI8
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BU of 8ri8 by Molmil
Beta-galactosidase (LacZ) in complex with synthetic glycosyrin.
Descriptor: (2S,3R,4S)-2-[bis(oxidanyl)methyl]pyrrolidine-3,4-diol, Beta-galactosidase, MAGNESIUM ION, ...
Authors:Hardenbrook, N.J, Sheng, Y, Zhang, P.
Deposit date:2023-12-18
Release date:2025-01-01
Last modified:2026-04-01
Method:ELECTRON MICROSCOPY (1.42 Å)
Cite:Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology.
Science, 388, 2025
8RI6
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BU of 8ri6 by Molmil
Beta-galactosidase (LacZ) purified from E. coli.
Descriptor: Beta-galactosidase, MAGNESIUM ION, SODIUM ION
Authors:Hardenbrook, N.J, Sheng, Y, Zhang, P.
Deposit date:2023-12-18
Release date:2025-01-01
Last modified:2026-04-01
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology.
Science, 388, 2025
9NEM
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BU of 9nem by Molmil
Structure of Unc119-Farnesylated peptide complex
Descriptor: FARNESYL, Protein unc-119 homolog A
Authors:Srivastava, D, Sebag, J.A, Artemyev, N.O.
Deposit date:2025-02-20
Release date:2025-09-03
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Inhibition of Unc119b improves insulin sensitivity through potentiation of Rac1 activation in skeletal muscle and brown adipose tissue.
Mol Metab, 100, 2025
9ODX
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BU of 9odx by Molmil
Structure of Unc119B in complex with N-acetyl-S-geranylgeranyl-L-Cysteine
Descriptor: N-acetyl-S-geranylgeranyl-L-cysteine, Protein unc-119 homolog B, SULFATE ION
Authors:Srivastava, D, Sebag, J.A, Artemyev, N.O.
Deposit date:2025-04-28
Release date:2025-09-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Inhibition of Unc119b improves insulin sensitivity through potentiation of Rac1 activation in skeletal muscle and brown adipose tissue.
Mol Metab, 100, 2025
7UMO
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BU of 7umo by Molmil
Structure of Unc119-inhibitor complex.
Descriptor: (3s,5s,7s)-N-(4,5-dichloropyridin-2-yl)adamantane-1-carboxamide, GLYCEROL, Protein unc-119 homolog A
Authors:Srivastava, D, Sebag, J.A, Artemyev, N.O.
Deposit date:2022-04-07
Release date:2023-07-26
Last modified:2026-03-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insulin sensitization by small molecules enhancing GLUT4 translocation.
Cell Chem Biol, 30, 2023

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