6Q8I

Nterminal domain of human SMU1 in complex with human REDmid

Summary for 6Q8I

• Entry DOI: 10.2210/pdb6q8i/pdb
• Related: 6Q8F
• Descriptor: WD40 repeat-containing protein SMU1, Protein Red (3 entities in total)
• Functional Keywords: splicing factor, minimal red-smu1 complex, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 16
• Total formula weight: 986937.96

Authors

Tengo, L.,Le Corre, L.,Fournier, G.,Ashraf, U.,Busca, P.,Rameix-Welti, M.-A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.-O.,Pietrancosta, N.,Naffakh, N.,McCarthy, A.A.,Crepin, T. (deposition date: 2018-12-14, release date: 2019-05-22, Last modification date: 2024-01-24)

• Primary citation: Ashraf, U.,Tengo, L.,Le Corre, L.,Fournier, G.,Busca, P.,McCarthy, A.A.,Rameix-Welti, M.A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.O.,Pietrancosta, N.,Crepin, T.,Naffakh, N.; Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.; Proc.Natl.Acad.Sci.USA, 116:10968-10977, 2019; PubMed: 31076555; DOI: 10.1073/pnas.1901214116

Experimental method

X-RAY DIFFRACTION (3.17 Å)