6Q8F
Nterminal domain of human SMU1
Summary for 6Q8F
Entry DOI | 10.2210/pdb6q8f/pdb |
Descriptor | WD40 repeat-containing protein SMU1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | splicing factor, splicing |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 115592.29 |
Authors | Tengo, L.,Le Corre, L.,Fournier, G.,Ashraf, U.,Busca, P.,Rameix-Welti, M.-A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.-O.,Pietrancosta, N.,Naffakh, N.,McCarthy, A.A.,Crepin, T. (deposition date: 2018-12-14, release date: 2019-05-22, Last modification date: 2024-05-15) |
Primary citation | Ashraf, U.,Tengo, L.,Le Corre, L.,Fournier, G.,Busca, P.,McCarthy, A.A.,Rameix-Welti, M.A.,Gravier-Pelletier, C.,Ruigrok, R.W.H.,Jacob, Y.,Vidalain, P.O.,Pietrancosta, N.,Crepin, T.,Naffakh, N. Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy. Proc.Natl.Acad.Sci.USA, 116:10968-10977, 2019 Cited by PubMed: 31076555DOI: 10.1073/pnas.1901214116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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