5VK2
| Structural basis for antibody-mediated neutralization of Lassa virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hastie, K.M, Zandonatti, M.A, Kleinfelter, L.M, Rowland, M.L, Rowland, M.M, Chandra, K, Branco, L.M, Robinson, J.E, Garry, R.F, Saphire, E.O. | Deposit date: | 2017-04-20 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Structural basis for antibody-mediated neutralization of Lassa virus. Science, 356, 2017
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6P91
| Structure of Lassa virus glycoprotein bound to Fab 18.5C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 18.5C Antibody heavy chain, ... | Authors: | Saphire, E.O, Hastie, K.M. | Deposit date: | 2019-06-09 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization. Cell, 178, 2019
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6P95
| Structure of Lassa virus glycoprotein in complex with Fab 25.6A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Saphire, E.O, Hastie, K.M. | Deposit date: | 2019-06-09 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization. Cell, 178, 2019
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7N6P
| Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | Descriptor: | 1C3 Fab heavy chain, 1C3 Fab light chain | Authors: | Milligan, J.C, Yu, X, Buck, T, Saphire, E.O. | Deposit date: | 2021-06-08 | Release date: | 2022-04-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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7UL7
| Lineage I (Pinneo) Lassa virus glycoprotein bound to 18.5C-M30 Fab | Descriptor: | 18.5C-M30 Fab Heavy Chain, 18.5C-M30 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Buck, T.K, Enriquez, A.S, Hastie, K.M. | Deposit date: | 2022-04-04 | Release date: | 2022-06-15 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Neutralizing Antibodies against Lassa Virus Lineage I. Mbio, 13, 2022
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7UOV
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7UOT
| Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 37.2D heavy chain (variable domain), ... | Authors: | Li, H, Saphire, E.O. | Deposit date: | 2022-04-13 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus. Sci Transl Med, 14, 2022
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7S8G
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7S8H
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7SWD
| Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound | Descriptor: | 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ... | Authors: | Milligan, J.C, Yu, X, Saphire, E.O. | Deposit date: | 2021-11-19 | Release date: | 2022-04-06 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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7TYV
| Structure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... | Authors: | Enriquez, A.S, Hastie, K.M. | Deposit date: | 2022-02-14 | Release date: | 2022-06-01 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies. Cell Rep, 39, 2022
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7UDS
| Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... | Authors: | Buck, T.K, Enriquez, A.E, Hastie, K.M. | Deposit date: | 2022-03-20 | Release date: | 2022-06-15 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Neutralizing Antibodies against Lassa Virus Lineage I. Mbio, 13, 2022
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