5VK2

Structural basis for antibody-mediated neutralization of Lassa virus

Summary for 5VK2

• Entry DOI: 10.2210/pdb5vk2/pdb
• Descriptor: Pre-glycoprotein polyprotein GP complex, Fab 37.7H heavy chain, Fab 37.7H light chain, ... (9 entities in total)
• Functional Keywords: lassa, glycoprotein, arenavirus, antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa virus (LASV); More
• Total number of polymer chains: 12
• Total formula weight: 299802.02

Authors

Hastie, K.M.,Zandonatti, M.A.,Kleinfelter, L.M.,Rowland, M.L.,Rowland, M.M.,Chandra, K.,Branco, L.M.,Robinson, J.E.,Garry, R.F.,Saphire, E.O. (deposition date: 2017-04-20, release date: 2017-05-31, Last modification date: 2023-10-04)

• Primary citation: Hastie, K.M.,Zandonatti, M.A.,Kleinfelter, L.M.,Heinrich, M.L.,Rowland, M.M.,Chandran, K.,Branco, L.M.,Robinson, J.E.,Garry, R.F.,Saphire, E.O.; Structural basis for antibody-mediated neutralization of Lassa virus.; Science, 356:923-928, 2017; PubMed: 28572385; DOI: 10.1126/science.aam7260

Experimental method

X-RAY DIFFRACTION (3.201 Å)