5VK2
Structural basis for antibody-mediated neutralization of Lassa virus
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH |
| Chain | Residue | Details |
| E | TYR196-HIS202 | |
| D | TYR205-HIS211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04084, ECO:0000269|PubMed:28572385 |
| Chain | Residue | Details |
| a | ASN365 | |
| a | ASN373 | |
| a | ASN390 | |
| a | ASN395 | |
| b | ASN365 | |
| b | ASN373 | |
| b | ASN390 | |
| b | ASN395 | |
| c | ASN365 | |
| c | ASN373 | |
| c | ASN390 | |
| c | ASN395 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 45 |
| Details | TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04084, ECO:0000269|PubMed:35173332 |
| Chain | Residue | Details |
| A | VAL18-LYS33 | |
| B | VAL18-LYS33 | |
| C | VAL18-LYS33 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 72 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04084, ECO:0000269|PubMed:35173332 |
| Chain | Residue | Details |
| A | GLY34-THR58 | |
| B | GLY34-THR58 | |
| C | GLY34-THR58 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04084 |
| Chain | Residue | Details |
| A | CYS57 | |
| B | CYS57 | |
| C | CYS57 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host signal peptidase => ECO:0000255|HAMAP-Rule:MF_04084 |
| Chain | Residue | Details |
| A | THR58 | |
| B | THR58 | |
| C | THR58 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host MBTPS1 => ECO:0000255|HAMAP-Rule:MF_04084 |
| Chain | Residue | Details |
| A | ARG259 | |
| B | ARG259 | |
| C | ARG259 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | LIPID: N-myristoyl glycine; by host => ECO:0000255|HAMAP-Rule:MF_04084 |
| Chain | Residue | Details |
| A | GLY2 | |
| B | GLY2 | |
| C | GLY2 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04084, ECO:0000269|PubMed:28572385 |
| Chain | Residue | Details |
| A | ASN79 | |
| A | ASN89 | |
| A | ASN99 | |
| B | ASN79 | |
| B | ASN89 | |
| B | ASN99 | |
| C | ASN79 | |
| C | ASN89 | |
| C | ASN99 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04084, ECO:0000269|PubMed:25972533, ECO:0000269|PubMed:26849049, ECO:0000269|PubMed:28572385 |
| Chain | Residue | Details |
| A | ASN109 | |
| A | ASN119 | |
| A | ASN167 | |
| A | ASN224 | |
| B | ASN109 | |
| B | ASN119 | |
| B | ASN167 | |
| B | ASN224 | |
| C | ASN109 | |
| C | ASN119 | |
| C | ASN167 | |
| C | ASN224 |
