8OTU
 
 | | The crystal structure of PET44, a PETase enzyme from Alkalilimnicola ehrlichii | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Dienelactone hydrolase domain-containing protein, ... | | Authors: | Costanzi, E, Applegate, V, Smits, S.H.J. | | Deposit date: | 2023-04-21 | | Release date: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The crystal structure of PET44, a PETase enzyme from Alkalilimnicola ehrlichii
To Be Published
|
|
7PZJ
 | | Structure of a bacteroidetal polyethylene terephthalate (PET) esterase | | Descriptor: | Lipase, POTASSIUM ION | | Authors: | Zang, H, Dierkes, R, Perez-Garcia, P, Weigert, S, Sternagel, S, Hallam, S.J, Applegate, V, Schumacher, J, Schott, T, Pleiss, J, Almeida, A, Hoecker, B, Smits, S.H, Schmitz, R.A, Chow, J, Streit, W.R. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity.
Front Microbiol, 12, 2021
|
|
9I09
 | | The Paulinella chromatophore transit peptide part2 (crTPpart2) of RnaH | | Descriptor: | N-PROPANOL, Transit peptide part2 (crTPpart2) | | Authors: | Klimenko, V, Reiners, J, Applegate, V, Reimann, K, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | | Deposit date: | 2025-01-14 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the gamma-glutamyl-cyclotransferase fold.
Plant Physiol., 199, 2025
|
|
9I08
 | | The Paulinella chromatophore transit peptide part2 (crTPpart2) from ArgC | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | | Authors: | Klimenko, V, Reiners, J, Applegate, V, Reimann, K, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | | Deposit date: | 2025-01-14 | | Release date: | 2025-11-19 | | Last modified: | 2026-02-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the gamma-glutamyl-cyclotransferase fold.
Plant Physiol., 199, 2025
|
|
9R8I
 | | sucrose hydrolase SuxB from Xanthomonas oryzae pv. oryzae | | Descriptor: | 1,2-ETHANEDIOL, Amylosucrase, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Zoellner, N, Applegate, V, Smits, S.H.J, Hoeppner, A. | | Deposit date: | 2025-05-16 | | Release date: | 2026-03-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A critical role of sux cistron-mediated sucrose uptake for virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Pnas Nexus, 5, 2026
|
|
9R9L
 | | sucrose hydrolase SuxB from Xanthomonas oryzae pv. oryzae in complex with glucose | | Descriptor: | Amylosucrase, POTASSIUM ION, alpha-D-glucopyranose | | Authors: | Zoellner, N, Applegate, V, Smits, S.H.J, Hoeppner, A. | | Deposit date: | 2025-05-20 | | Release date: | 2026-03-25 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | A critical role of sux cistron-mediated sucrose uptake for virulence of the rice blight pathogen Xanthomonas oryzae pv. oryzae.
Pnas Nexus, 5, 2026
|
|
8B6E
 | | crystal structure of the DNA-binding short chromatophore-targeted protein sCTP-23166 from Paulinella chromatophora | | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, sCTP-23166 | | Authors: | Macorano, L, Applegate, V, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | | Deposit date: | 2022-09-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7AT5
 | | Structure of protein kinase ck2 catalytic subunit (csnk2a1 gene product) in complex with the bivalent inhibitor KN2 | | Descriptor: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, Casein kinase II subunit alpha, ... | | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | | Deposit date: | 2020-10-29 | | Release date: | 2021-08-04 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity.
J.Med.Chem., 65, 2022
|
|
7AT9
 | | Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the ATP-competitive inhibitor MB002 and the alphaD-pocket ligand 3,4-dichlorophenethylamine | | Descriptor: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, ... | | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | | Deposit date: | 2020-10-29 | | Release date: | 2021-08-04 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity.
J.Med.Chem., 65, 2022
|
|
7ATV
 | | Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the bivalent inhibitor KN2 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Casein kinase II subunit alpha', ... | | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | | Deposit date: | 2020-10-31 | | Release date: | 2021-08-04 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (0.98 Å) | | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity.
J.Med.Chem., 65, 2022
|
|
8A2C
 | | The crystal structure of the S178A mutant of PET40, a PETase enzyme from an unclassified Amycolatopsis | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | | Authors: | Costanzi, E, Applegate, V, Port, A, Smits, S.H.J. | | Deposit date: | 2022-06-03 | | Release date: | 2023-06-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).
Febs J., 291, 2024
|
|
8B4U
 | | The crystal structure of PET46, a PETase enzyme from Candidatus bathyarchaeota | | Descriptor: | 1,2-ETHANEDIOL, Alpha/beta hydrolase, CHLORIDE ION, ... | | Authors: | Costanzi, E, Applegate, V, Schumacher, J, Smits, S.H.J. | | Deposit date: | 2022-09-21 | | Release date: | 2023-08-23 | | Last modified: | 2026-03-04 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate.
Commun Chem, 6, 2023
|
|
8S65
 | | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) as target for anti Toxoplasma gondii compounds: crystal structure, biochemical characterization and biological evaluation of inhibitors | | Descriptor: | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, CHLORIDE ION, ... | | Authors: | Mazzone, F, Hoeppner, A, Reiners, J, Applegate, V, Abdullaziz, M, Gottstein, J, Wesemann, M, Kurz, T, Smits, S.H, Pfeffer, K. | | Deposit date: | 2024-02-26 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-04 | | Method: | SOLUTION SCATTERING (2.56 Å), X-RAY DIFFRACTION | | Cite: | 1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors.
Biochem.J., 481, 2024
|
|
8S5R
 | | Structure of the Chlamydia pneumoniae effector SemD | | Descriptor: | Effector SemD | | Authors: | Kocher, F, Applegate, V, Reiners, J, Port, A, Spona, D, Haensch, S, Smits, S.H, Hegemann, J, Moelleken, K. | | Deposit date: | 2024-02-25 | | Release date: | 2024-08-07 | | Last modified: | 2025-02-19 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Chlamydia pneumoniae effector SemD exploits its host's endocytic machinery by structural and functional mimicry.
Nat Commun, 15, 2024
|
|
8S5T
 | | Structure of SemD in complex | | Descriptor: | Effector SemD, Neural Wiskott-Aldrich syndrome protein | | Authors: | Kocher, F, Applegate, V, Port, A, Reiners, J, Spona, D, Haensch, S, Smits, S.H, Hegemann, J, Moelleken, K. | | Deposit date: | 2024-02-25 | | Release date: | 2024-08-07 | | Last modified: | 2025-02-19 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The Chlamydia pneumoniae effector SemD exploits its host's endocytic machinery by structural and functional mimicry.
Nat Commun, 15, 2024
|
|
