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6LJM
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BU of 6ljm by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P13
Descriptor: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-SER-LEU-GLY-SLL, NAD-dependent protein deacylase sirtuin-5, ...
Authors:Chen, Q, Yu, Y.
Deposit date:2019-12-17
Release date:2020-10-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6LJN
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BU of 6ljn by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P15
Descriptor: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-HIS-PHE-SER-SLL, NAD-dependent protein deacylase sirtuin-5, ...
Authors:Chen, Q, Yu, Y.
Deposit date:2019-12-17
Release date:2020-10-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6LJK
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BU of 6ljk by Molmil
Crystal structure of human Sirt5 in complex with an internally quenched fluorescent substrate GluIQF
Descriptor: BE2-SER-ALA-ILE-LYS-SER-NIY-GLY-SET, GLUTARIC ACID, NAD-dependent protein deacylase sirtuin-5, ...
Authors:Chen, Q, Yu, Y.
Deposit date:2019-12-17
Release date:2020-12-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.394 Å)
Cite:Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
7XF3
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BU of 7xf3 by Molmil
The structure of HLA-B*1501/BM58-66AF9
Descriptor: 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen
Authors:Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L.
Deposit date:2022-03-31
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape.
J Immunol., 210, 2023
8GUO
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BU of 8guo by Molmil
Crystal structure of the nuclease domain of EsaD in complex with EsaG from Staphylococcus aureus
Descriptor: Type VII secretion system protein EsaG, Type VII secretion system protein EssD
Authors:Zhang, Z.M, Wang, Y.J.
Deposit date:2022-09-13
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5939517 Å)
Cite:A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
8GUP
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BU of 8gup by Molmil
Crystal structure of EsaG from Staphylococcus aureus
Descriptor: CITRIC ACID, Type VII secretion system protein EsaG
Authors:Zhang, Z.M, Wang, Y.J.
Deposit date:2022-09-13
Release date:2022-11-09
Method:X-RAY DIFFRACTION (2.298725 Å)
Cite:A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
8GUN
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BU of 8gun by Molmil
Crystal structure of mutant H528A of EsaD from Staphylococcus aureus
Descriptor: MAGNESIUM ION, Type VII secretion system protein EssD
Authors:Zhang, Z.M, Wang, Y.J.
Deposit date:2022-09-13
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.30001378 Å)
Cite:A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
7FAQ
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BU of 7faq by Molmil
Crystal structure of PDE5A in complex with inhibitor L1
Descriptor: 2-[(4-chlorophenyl)methyl]-5-methoxy-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one, MAGNESIUM ION, SULFATE ION, ...
Authors:Wu, D, Huang, Y.Y, Luo, H.B.
Deposit date:2021-07-07
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.200136 Å)
Cite:Free energy perturbation (FEP)-guided scaffold hopping.
Acta Pharm Sin B, 12, 2022
7FAR
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BU of 7far by Molmil
Crystal structure of PDE5A in complex with inhibitor L12
Descriptor: 5-[bis(fluoranyl)methoxy]-2-[(4-chlorophenyl)methyl]-10-(3-methoxypropyl)-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one, MAGNESIUM ION, ZINC ION, ...
Authors:Wu, D, Huang, Y.Y, Luo, H.B.
Deposit date:2021-07-07
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.40006471 Å)
Cite:Free energy perturbation (FEP)-guided scaffold hopping.
Acta Pharm Sin B, 12, 2022
7Y73
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BU of 7y73 by Molmil
Crystal structure of sDscam Ig1 domain, isoform beta3v7
Descriptor: Down Syndrome Cell Adhesion Molecules, GLYCEROL
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-21
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8I
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BU of 7y8i by Molmil
Crystal structure of sDscam FNIII3 domain, isoform alpha7
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ...
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y9A
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BU of 7y9a by Molmil
Crystal structure of sDscam Ig1-2 domains, isoform beta2v6
Descriptor: Down Syndrome Cell Adhesion Molecules, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)][beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5J
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BU of 7y5j by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha1v7
Descriptor: Down Syndrome Cell Adhesion Molecules
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-17
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8S
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BU of 7y8s by Molmil
Crystal structure of sDscam FNIII1-3 domains, isoform beta2v6
Descriptor: Dscam, SODIUM ION
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6O
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BU of 7y6o by Molmil
Crystal structure of sDscam Ig1-3 domains, isoform alpha25
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecules
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-21
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y54
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BU of 7y54 by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha1
Descriptor: Down Syndrome Cell Adhesion Molecules
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-16
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.787 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5R
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BU of 7y5r by Molmil
Crystal structure of sDscam FNIII2 domain, isoform alpha7
Descriptor: Down Syndrome Cell Adhesion Molecules, GLYCEROL
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-17
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.562 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y4X
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BU of 7y4x by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-16
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.952 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6E
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BU of 7y6e by Molmil
Crystal structure of sDscam FNIII23 domains, isoform Beta2v6
Descriptor: Dscam
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-20
Release date:2023-05-24
Method:X-RAY DIFFRACTION (3.034 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y95
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BU of 7y95 by Molmil
Crystal structure of sDscam Ig1 domain, isoform beta6v2
Descriptor: Dscam, GLYCEROL, SODIUM ION
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8H
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BU of 7y8h by Molmil
Crystal structure of sDscam FNIII1 domain, isoform alpha7
Descriptor: Down Syndrome Cell Adhesion Molecules, SULFATE ION
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-23
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
8HN9
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BU of 8hn9 by Molmil
Human SIRT3 Recognizing CCNE2K348la peptide
Descriptor: CCNE2 peptide, IMIDAZOLE, NAD-dependent protein deacetylase sirtuin-3, ...
Authors:Wang, Y, Ding, W.
Deposit date:2022-12-07
Release date:2023-05-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth.
Embo Rep., 24, 2023
7VS2
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BU of 7vs2 by Molmil
secreted fungal effector protein MoErs1
Descriptor: MoErs1
Authors:Wang, F.F, Xing, W.M.
Deposit date:2021-10-25
Release date:2023-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast.
Nat.Plants, 2024
7X8C
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BU of 7x8c by Molmil
Crystal structure of a KTSC family protein from Euryarchaeon Methanolobus vulcani
Descriptor: KTSC domain-containing protein, SODIUM ION
Authors:Zhang, Z.F, Zhu, K.L, Chen, Y.Y, Cao, P, Gong, Y.
Deposit date:2022-03-12
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Biochemical and structural characterization of a KTSC family single-stranded DNA-binding protein from Euryarchaea.
Int.J.Biol.Macromol., 216, 2022
7YI4
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BU of 7yi4 by Molmil
Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state
Descriptor: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023

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