4K7K
 
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6OR2
 | | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine | | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, DODECYL-BETA-D-MALTOSIDE, Membrane protein, ... | | Authors: | Su, C.-C. | | Deposit date: | 2019-04-29 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OWS
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4K34
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6VQQ
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3HGG
 | | Crystal Structure of CmeR Bound to Cholic Acid | | Descriptor: | CHOLIC ACID, CmeR | | Authors: | Routh, M.D, Yang, F. | | Deposit date: | 2009-05-13 | | Release date: | 2010-06-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural basis for anionic ligand recognition by multidrug
binding proteins: Crystal structures of CmeR-bile acid complexes
To be Published
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6VKS
 | | Cryo-electron microscopy structures of a gonococcal multidrug efflux pump illuminate a mechanism of drug recognition with ampicillin | | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE | | Authors: | Moseng, M.A, Lyu, M. | | Deposit date: | 2020-01-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance.
Mbio, 11, 2020
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3HGY
 | | Crystal Structure of CmeR Bound to Taurocholic Acid | | Descriptor: | CmeR, TAUROCHOLIC ACID | | Authors: | Routh, M.D, Yang, F. | | Deposit date: | 2009-05-14 | | Release date: | 2010-06-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.416 Å) | | Cite: | Structural basis for anionic ligand recognition by multidrug
binding proteins: crystal structures of CmeR-bile acid complexes
To be Published
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6VKT
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6VQR
 | | CryoEM Structure of the PfFNT-inhibitor complex | | Descriptor: | (2R)-2-hydroxy-7-methoxy-2-(pentafluoroethyl)-2,3-dihydro-4H-1-benzopyran-4-one, Formate-nitrite transporter | | Authors: | Su, C.C, Lyu, M. | | Deposit date: | 2020-02-05 | | Release date: | 2021-02-03 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Structural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT.
Embo Rep., 22, 2021
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6WTI
 | | The Cryo-EM structure of the ubiquinol oxidase from Escherichia coli | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome o ubiquinol oxidase, ... | | Authors: | Su, C.-C. | | Deposit date: | 2020-05-02 | | Release date: | 2021-01-20 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.38 Å) | | Cite: | A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
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3K0I
 | | Crystal structure of Cu(I)CusA | | Descriptor: | COPPER (I) ION, Cation efflux system protein cusA | | Authors: | Su, C.-C. | | Deposit date: | 2009-09-24 | | Release date: | 2010-10-13 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.116 Å) | | Cite: | Crystal structure of CusA
To be Published
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3K07
 | | Crystal structure of CusA | | Descriptor: | Cation efflux system protein cusA | | Authors: | Su, C.-C. | | Deposit date: | 2009-09-24 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.521 Å) | | Cite: | Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
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3KSO
 | | Structure and Mechanism of the Heavy Metal Transporter CusA | | Descriptor: | Cation efflux system protein cusA, SILVER ION | | Authors: | Su, C.-C. | | Deposit date: | 2009-11-23 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.367 Å) | | Cite: | Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
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3KSS
 | | Structure and Mechanism of the Heavy Metal Transporter CusA | | Descriptor: | COPPER (I) ION, Cation efflux system protein cusA | | Authors: | Su, C.-C. | | Deposit date: | 2009-11-23 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.88 Å) | | Cite: | Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport.
Nature, 467, 2010
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5U9O
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5U9L
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8DNS
 | | Human Brain Glyceraldehyde 3-phosphate dehydrogenase | | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase | | Authors: | Tringides, M.L. | | Deposit date: | 2022-07-11 | | Release date: | 2022-11-16 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
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8DNO
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8DNP
 | | Human Brain Ferritin Heavy Chain | | Descriptor: | FE (III) ION, Ferritin heavy chain | | Authors: | Tringides, M.L. | | Deposit date: | 2022-07-11 | | Release date: | 2022-11-16 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
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8DNU
 | | Human Brain Glutamine Synthetase | | Descriptor: | Glutamine synthetase, MANGANESE (II) ION | | Authors: | Tringides, M.L. | | Deposit date: | 2022-07-11 | | Release date: | 2022-11-16 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
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8DNM
 | | Human Brain Dihydropyrimidinase-related protein 2 | | Descriptor: | Dihydropyrimidinase-related protein 2 | | Authors: | Tringides, M.L. | | Deposit date: | 2022-07-11 | | Release date: | 2022-11-16 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
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8EOR
 | | Liver carboxylesterase 1 | | Descriptor: | ETHYL ACETATE, Liver carboxylesterase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Zhang, Z, Yu, E. | | Deposit date: | 2022-10-04 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
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7SFL
 | | Human NKCC1 state Fu-II | | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-10-04 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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7SMP
 | | CryoEM structure of NKCC1 Bu-I | | Descriptor: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-10-26 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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