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4Z8N
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BU of 4z8n by Molmil
Crystal structure of the erythrocyte-binding domain from Plasmodium vivax reticulocyte-binding protein 2a (PvRBP2a)
分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Gruszczyk, J, Tham, W.H.
登録日2015-04-09
公開日2015-12-16
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.124 Å)
主引用文献Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement.
Proc.Natl.Acad.Sci.USA, 113, 2016
7RR0
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BU of 7rr0 by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 222
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ...
著者Pymm, P, Glukhova, A, Black, K.A, Tham, W.H.
登録日2021-08-08
公開日2021-10-06
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
6D03
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BU of 6d03 by Molmil
Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; one molecule of parasite ligand.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(2-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gruszczyk, J, Huang, R.K, Hong, C, Yu, Z, Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D05
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BU of 6d05 by Molmil
Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 2.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Gruszczyk, J, Huang, R.K, Hong, C, Yu, Z, Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D04
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BU of 6d04 by Molmil
Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Gruszczyk, J, Huang, R.K, Hong, C, Yu, Z, Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6WM9
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BU of 6wm9 by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 237235
分子名称: 237235 Fab heavy chain, 237235 Fab light chain, Reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-04-20
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTU
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BU of 6wtu by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 273264
分子名称: 273264 Fab heavy chain, 273264 Fab light chain, reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-05-04
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WN1
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BU of 6wn1 by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 241242
分子名称: 241242 Fab heavy chain, 241242 Fab light chain, Reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-04-22
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
7KJI
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BU of 7kji by Molmil
Plasmodium falciparum protein Pf12p bound to nanobody D9
分子名称: Nanobody D9, Surface protein P12p
著者Dietrich, M.H, Tham, W.H.
登録日2020-10-26
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
7KJ7
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BU of 7kj7 by Molmil
Plasmodium falciparum protein Pf12p
分子名称: Surface protein P12p
著者Dietrich, M.H, Tham, W.H.
登録日2020-10-26
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
6WQO
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BU of 6wqo by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 283284
分子名称: 283284 Fab heavy chain, 283284 Fab light chain, reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-04-29
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
7KJH
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BU of 7kjh by Molmil
Plasmodium falciparum protein Pf12p bound to nanobody B9
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Nanobody B9, ...
著者Dietrich, M.H, Tham, W.H.
登録日2020-10-26
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
6WNO
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BU of 6wno by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 243244
分子名称: 243244 Fab heavy chain, 243244 Fab light chain, Plasmodium vivax reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-04-23
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTV
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BU of 6wtv by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 258259
分子名称: 258259 Fab heavy chain, 258259 Fab light chain, reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-05-04
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTY
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BU of 6wty by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 253245
分子名称: 253245 Fab heavy chain, 253245 Fab light chain, reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-05-04
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.481 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WOZ
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BU of 6woz by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 251249
分子名称: 251249 Fab heavy chain, 251249 Fab light chain, reticulocyte binding protein 2b
著者Chan, L.J, Dietrich, M.H, Tham, W.H.
登録日2020-04-26
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
7LDJ
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BU of 7ldj by Molmil
SARS-CoV-2 receptor binding domain in complex with WNb-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 2, ...
著者Pymm, P, Dietrich, M.H, Tan, L.L, Adair, A, Tham, W.H.
登録日2021-01-13
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献SARS-CoV-2 receptor binding domain in complex with WNb-2
Proc.Natl.Acad.Sci.USA, 2021
6BPD
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BU of 6bpd by Molmil
Plasmodium vivax invasion blocking monoclonal antibody 10B12
分子名称: Monoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPB
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BU of 6bpb by Molmil
Plasmodium vivax invasion blocking monoclonal antibody 4F7
分子名称: Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPC
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BU of 6bpc by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 4F7
分子名称: Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain, Reticulocyte binding protein 2, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPA
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BU of 6bpa by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 3E9
分子名称: BROMIDE ION, Monoclonal antibody 3E9 Fab heavy chain, Monoclonal antibody 3E9 Fab light chain, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPE
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BU of 6bpe by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 6H1
分子名称: Monoclonal antibody 6H1 Fab heavy chain, Monoclonal antibody 6H1 Fab light chain, Reticulocyte binding protein 2, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
7S7R
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BU of 7s7r by Molmil
Plasmodium falciparum protein Pf12 bound to nanobody G7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Merozoite surface protein P12, Nanobody G7, ...
著者Dietrich, M.H, Tham, W.H.
登録日2021-09-17
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins.
FEMS Microbes, 3, 2022
7USV
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BU of 7usv by Molmil
Plasmodium falciparum protein Pfs230 D1 in complex with nanobody F10
分子名称: Gametocyte surface protein P230, Nanobody F10, SULFATE ION
著者Dietrich, M.H, Tham, W.H.
登録日2022-04-25
公開日2022-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022
7USS
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BU of 7uss by Molmil
Plasmodium falciparum protein Pfs230 Pro-D1D2 - Structure of the first two 6-cysteine domains with N-terminal extension
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P230, ...
著者Dietrich, M.H, Tham, W.H.
登録日2022-04-25
公開日2022-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022

 

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