6BPD

Plasmodium vivax invasion blocking monoclonal antibody 10B12

Summary for 6BPD

Related6BPA 6BPB 6BPC 6BPE
DescriptorMonoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain (3 entities in total)
Functional Keywordsplasmodium vivax, invasion, malaria, antibody, immune system
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight52182.37
Authors
Gruszczyk, J.,Chan, L.J.,Tham, W.H. (deposition date: 2017-11-22, release date: 2018-06-20, Last modification date: 2018-07-18)
Primary citation
Gruszczyk, J.,Huang, R.K.,Chan, L.J.,Menant, S.,Hong, C.,Murphy, J.M.,Mok, Y.F.,Griffin, M.D.W.,Pearson, R.D.,Wong, W.,Cowman, A.F.,Yu, Z.,Tham, W.H.
Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559:135-139, 2018
PubMed: 29950717 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0249-1
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.32 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.265141.6%2.3%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6bpd
no rotation
Molmil generated image of 6bpd
rotated about x axis by 90°
Molmil generated image of 6bpd
rotated about y axis by 90°